Kawasaki disease, also known as mucocutaneous lymph node syndrome, has an unclear pathogenesis. Its pathological changes primarily involve a systemic circulatory disease characterized by vasculitis. A severe complication can lead to cardiac lesions. Generally, Kawasaki disease is self-limiting and most cases have a good prognosis. However, if Kawasaki disease is not effectively treated and results in associated coronary artery aneurysms or large artery aneurysms, it could lead to acquired heart disease. Such cardiac issues could potentially affect cardiac function later on. This might impact lifespan, but if Kawasaki disease is treated aggressively and effectively, the prognosis is good and the impact on future health is minimal.