How to treat Helicobacter pylori positive?

Written by Si Li Li
Gastroenterology
Updated on November 12, 2024
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The infection rate of Helicobacter pylori in our country has already exceeded 50%, and Helicobacter pylori has been confirmed as the main cause of chronic gastritis, peptic ulcers, and even gastric cancer. If Helicobacter pylori tests positive and is accompanied by symptoms or diseases of the digestive system, eradication treatment for Helicobacter pylori is necessary. The medication involves a proton pump inhibitor, two types of antibiotics, and a bismuth agent, with a treatment period of 14 days. After the 14-day treatment, the medication should be discontinued for a month before rechecking with a carbon-14 breath test to confirm whether Helicobacter pylori has turned negative. If it has turned negative, it indicates that the eradication treatment of Helicobacter pylori is successful. After infection with Helicobacter pylori, a diet easy to digest is recommended.

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Written by Wu Hai Wu
Gastroenterology
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Is the treatment process for Helicobacter pylori uncomfortable?

The treatment process for Helicobacter pylori infection is not uncomfortable, primarily involving oral medication. Treatment options include a combination of two antibiotics such as amoxicillin, clarithromycin, furazolidone, metronidazole, etc., alongside a proton pump inhibitor like omeprazole, pantoprazole, or lansoprazole, and the addition of bismuth citrate. This forms a quadruple therapy administered over two weeks to eradicate the infection. During treatment for Helicobacter pylori infection, it is advised to consume a diet rich in vitamins, incorporating fresh vegetables and fruits. It is important to eat regularly, avoid overeating or consuming oily, spicy, and irritating foods. (Please follow medical advice when using medications.)

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Written by Yang Chun Guang
Gastroenterology
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Can a gastroscopy detect Helicobacter pylori?

The examination with a gastroscope mainly focuses on checking for any damage to the mucous membranes of the stomach and esophagus. It can detect gastritis, gastric ulcers, or stomach cancer. For some patients who might have a tendency toward cancerous changes, a pathological examination can be conducted. However, testing for Helicobacter pylori with a gastroscope requires a separate lab test. Therefore, routine gastroscopic examinations generally do not include testing for Helicobacter pylori. If testing for Helicobacter pylori is needed, it is a separate examination item. Nowadays, since undergoing a gastroscopy can be quite uncomfortable and cause symptoms like nausea for some people, testing for Helicobacter pylori is accurately conducted using a breath test.

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Written by Wu Hai Wu
Gastroenterology
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Why is there an increase in flatulence after the treatment of Helicobacter pylori?

After treatment for Helicobacter pylori, having more flatulence generally isn't directly related to the treatment, as the medication used includes proton pump inhibitors, antibiotics such as amoxicillin, clarithromycin, as well as bismuth citrate potassium. None of these drugs typically cause increased flatulence. If a patient experiences more flatulence after treatment, it might be due to functional dyspepsia. At this point, treating the condition with medications that regulate the gut flora, such as combined lactobacilli and Bifidobacterium triple live bacteria, might be effective. If the increased flatulence persists, it is advisable to promptly undergo a digital colonoscopy to rule out the possibility of organic intestinal diseases. (Specific medications should be used under the guidance of a doctor.)

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Written by Wu Hai Wu
Gastroenterology
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Can treatment for Helicobacter pylori be stopped at any time?

During the treatment of Helicobacter pylori, it is not advisable to stop the medication arbitrarily, as doing so may lead to insufficient treatment duration and result in a failure to eradicate the bacteria. Therefore, it is recommended to use a bismuth-containing quadruple therapy for two weeks to eradicate Helicobacter pylori. The specific medications included in this two-week quadruple therapy are a proton pump inhibitor such as pantoprazole or lansoprazole, plus two antibiotics such as amoxicillin, clarithromycin, or metronidazole, combined with bismuth potassium citrate. The medication should be taken under medical supervision. Helicobacter pylori infection can be detected through a carbon-13 breath test or a carbon-14 breath test.

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Written by Si Li Li
Gastroenterology
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Can Helicobacter pylori infection heal itself?

Helicobacter pylori infection generally does not heal on its own. Currently, the infection rate of Helicobacter pylori in our country has exceeded 50%, which is very high. After being infected with Helicobacter pylori, most patients do not show any symptoms. However, some patients may develop chronic gastritis, peptic ulcer, and even stomach cancer due to Helicobacter pylori infection, presenting symptoms such as upper abdominal pain, belching, acid reflux, nausea, vomiting, and indigestion. These patients need to undergo gastroscopy to confirm the diagnosis. Additionally, eradication treatment for Helicobacter pylori is required, involving a proton pump inhibitor plus two antibiotics, along with a bismuth agent, totaling 14 days of treatment. If eradication treatment for Helicobacter pylori is not conducted, Helicobacter pylori will not heal on its own.