Can treatment for Helicobacter pylori be stopped at any time?

Written by Wu Hai Wu
Gastroenterology
Updated on February 18, 2025
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During the treatment of Helicobacter pylori, it is not advisable to stop the medication arbitrarily, as doing so may lead to insufficient treatment duration and result in a failure to eradicate the bacteria. Therefore, it is recommended to use a bismuth-containing quadruple therapy for two weeks to eradicate Helicobacter pylori. The specific medications included in this two-week quadruple therapy are a proton pump inhibitor such as pantoprazole or lansoprazole, plus two antibiotics such as amoxicillin, clarithromycin, or metronidazole, combined with bismuth potassium citrate. The medication should be taken under medical supervision. Helicobacter pylori infection can be detected through a carbon-13 breath test or a carbon-14 breath test.

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Written by Peng Miao Yun
Internal Medicine
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Symptoms of Helicobacter pylori infection

Helicobacter pylori, once settled in the stomach and duodenum, can cause chronic inflammation of the gastric mucosa, leading to reduced stomach digestive function. Over time, this may lead to chronic gastritis, gastric ulcers, and even cause gastric cancer. So, what are the symptoms of Helicobacter pylori infection? In cases of mild infection, where the bacteria count is low, there might be no obvious symptoms, with only bad breath occurring. If a high bacteria count causes an inflammatory reaction in the gastric mucosa, symptoms can include stomach bloating, stomach pain, acid reflux, a feeling of fullness in the stomach, along with nausea and bad breath.

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Written by Wu Hai Wu
Gastroenterology
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Is the treatment process for Helicobacter pylori uncomfortable?

The treatment process for Helicobacter pylori infection is not uncomfortable, primarily involving oral medication. Treatment options include a combination of two antibiotics such as amoxicillin, clarithromycin, furazolidone, metronidazole, etc., alongside a proton pump inhibitor like omeprazole, pantoprazole, or lansoprazole, and the addition of bismuth citrate. This forms a quadruple therapy administered over two weeks to eradicate the infection. During treatment for Helicobacter pylori infection, it is advised to consume a diet rich in vitamins, incorporating fresh vegetables and fruits. It is important to eat regularly, avoid overeating or consuming oily, spicy, and irritating foods. (Please follow medical advice when using medications.)

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Written by Wu Hai Wu
Gastroenterology
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Is it normal to experience vomiting during the treatment process for Helicobacter pylori?

During the treatment of Helicobacter pylori, vomiting may occur because the treatment to eradicate Helicobacter pylori involves the use of antibiotics such as clarithromycin and metronidazole. These antibiotics can irritate the gastrointestinal tract. Patients with stronger reactions may experience vomiting during the medication process. Therefore, it is recommended to take clarithromycin and metronidazole about half an hour after a meal. During the treatment period, patients infected with Helicobacter pylori should avoid spicy and irritating foods, drink more water, and consume light and easily digestible foods.

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Written by Wu Hai Wu
Gastroenterology
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How long does Helicobacter pylori resistance last?

Helicobacter pylori resistance generally develops around two weeks. If Helicobacter pylori shows resistance, it is advisable to consider adjusting the treatment using other antibiotics. The eradication treatment for Helicobacter pylori infection generally involves a two-week quadruple therapy with a bismuth-containing regimen. Furthermore, one month after stopping the eradication treatment, it is necessary to recheck with a carbon-13 breath test or a carbon-14 breath test to confirm effective eradication. Helicobacter pylori infection can cause gastritis, peptic ulcers, and malignant tumors in the stomach, among other issues.

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Written by Si Li Li
Gastroenterology
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How to treat Helicobacter pylori infection?

Helicobacter pylori has been confirmed as a major cause of chronic gastritis, peptic ulcers, and even gastric cancer. The infection rate of Helicobacter pylori in China is very high, exceeding 50%. It is related to the dietary structure in China, often linked significantly to the practice of sharing dishes during meals, which correlates with China's dietary habits. If someone tests positive for Helicobacter pylori and has symptoms of gastrointestinal disorders, such as indigestion, stomach pain, or bloating, then it is necessary to undergo treatment for Helicobacter pylori. The current standard treatment for Helicobacter pylori involves quadruple therapy: a proton pump inhibitor, two types of antibiotics, and a bismuth agent. This combination of medications is administered over a period of 14 days, representing the standardized treatment for Helicobacter pylori.