If Helicobacter pylori infection has not been cured after two treatments, it is necessary to consider the possibility of bacterial resistance or that the treatment was not standardized. It is advisable to visit the gastroenterology department of a hospital. Based on the doctor's experience, it may be necessary to adjust the medication plan. The choice of specific medications and their dosage should be determined according to the doctor's prescription. During the treatment period, one should eat easily digestible food and avoid spicy and irritating foods, as well as avoid drinking alcohol, strong tea, coffee, etc. It is also important to eat slowly and avoid overeating or drinking excessively.