Pleurisy is caused by what?

Written by An Yong Peng
Pulmonology
Updated on February 11, 2025
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Pleurisy is often caused by various pathogens, such as viral infections, which can lead to pleurisy termed viral pleurisy. Viral pleurisy typically presents with noticeable chest pain, and may even be accompanied by tenderness in the chest wall. Similarly, bacterial infections can also cause pleurisy. If the infection is a purulent bacterial infection, it is known as purulent pleurisy. Generally, those with purulent pleurisy experience high fever symptoms. Another common cause of pleurisy is tuberculosis infection, known as tuberculous pleurisy. Typical symptoms of tuberculous pleurisy include low-grade fever in the afternoon, night sweats, and may also include chest tightness and chest pain.

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Written by Wang Chun Mei
Pulmonology
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Does pleural calcification easily turn into cancer?

Pleurisy is a very common type of inflammatory lesion clinically. There are many factors that cause pleurisy, and it is generally seen in young and middle-aged males, mainly caused by Mycobacterium tuberculosis infection of the pleural cavity. If the pleurisy is tuberculous, it is usually treated with effective anti-tuberculosis medications systematically, which typically requires a course of 6 to 9 months. After complete recovery from pleurisy, many patients may show varying degrees of calcification spots in the pleural cavity. Generally, these calcification spots after recovery from pleurisy do not easily become cancerous.

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Written by Wang Chun Mei
Pulmonology
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Is it normal to occasionally feel chest tightness with pleuritis?

Patients with pleurisy occasionally experience chest tightness, which is a very common clinical symptom. It is important to clarify that in clinical cases, pleurisy is mostly due to infection of the pleural cavity by Mycobacterium tuberculosis, causing clinical symptoms such as fever, chest tightness, shortness of breath, cough, and chest pain. Therefore, during an acute episode of pleurisy, some patients may have a severe pleural infection, and possibly a large amount of pleural effusion, which inevitably leads to symptoms like shortness of breath and chest tightness. For patients with pleurisy, if it is tuberculous, it is crucial to provide anti-tuberculosis medication as early as possible for symptomatic treatment. A lengthy course of treatment is usually required to effectively control the discomfort caused by pleurisy.

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Written by Wang Chun Mei
Pulmonology
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Does pleurisy cause chest pain?

Pleurisy can cause anterior chest pain. It is a very common clinical disease, mostly caused by bacterial invasion of the pleura resulting in inflammatory lesions, with Mycobacterium tuberculosis being the most common pathogen. Due to inflammatory exudation, some patients may also experience varying degrees of pleural effusion. The clinical symptoms presented by patients mainly include fever, cough, shortness of breath, chest tightness, and chest pain. In severe cases, different levels of breathing difficulties and other clinical symptoms may occur. Therefore, it is very common for patients with pleurisy to experience anterior chest pain.

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Written by Yuan Qing
Pulmonology
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Sequelae of pleurisy with pulmonary effusion

The main sequelae of pleurisy with pleural effusion are pleural adhesions, which can affect respiratory function. Pleurisy is mostly caused by infectious diseases, although a portion is also due to non-infectious diseases. In the case of pleural effusion caused by infectious diseases, it contains a large amount of fibrinogen, which has the function of adhering to our pleura, thereby causing the pleura to thicken. At this time, the pleura will compress our lungs, significantly reducing the respiratory volume of our lungs, which greatly affects our respiratory function. Patients mainly exhibit symptoms such as shortness of breath, chest tightness, and rapid breathing even with slight activity or while lying in bed. Therefore, if pleurisy is detected, it is crucial to drain the fluid from the patient as soon as possible to avoid delaying treatment and the subsequent development of severe sequelae.

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Written by Liao Bin
Pulmonology
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How to determine if it is pleurisy.

Determining whether it is pleurisy can be analyzed from the following points. First, regarding clinical symptoms, patients with pleurisy often experience pleuritic chest pain, that is, pain in the chest and rib area on the affected side during deep breathing or coughing, or an exacerbation of the pain. At this point, it is important to specifically exclude the formation of pleurisy. Of course, patients with pleurisy may sometimes also experience varying degrees of coughing, and some patients may also have a fever. As the condition of pleurisy progresses, pleural effusion gradually forms, and this type of pleuritic chest pain gradually reduces, which requires careful differential diagnosis. Patients with pleurisy also need to undergo chest X-ray or CT scans, especially chest CT scans which can reveal pleural thickening and sometimes the formation of a small amount of pleural effusion. At this stage, a diagnosis of pleurisy can be confirmed. Therefore, the diagnosis of pleurisy must be made in conjunction with its specific clinical symptoms and chest imaging studies to make a precise determination.