Does pleural calcification easily turn into cancer?

Written by Wang Chun Mei

Pulmonology

Updated on February 11, 2025

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Pleurisy is a very common type of inflammatory lesion clinically. There are many factors that cause pleurisy, and it is generally seen in young and middle-aged males, mainly caused by Mycobacterium tuberculosis infection of the pleural cavity. If the pleurisy is tuberculous, it is usually treated with effective anti-tuberculosis medications systematically, which typically requires a course of 6 to 9 months. After complete recovery from pleurisy, many patients may show varying degrees of calcification spots in the pleural cavity. Generally, these calcification spots after recovery from pleurisy do not easily become cancerous.

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Written by Wang Chun Mei

Pulmonology

1min 5sec

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Is it normal to occasionally feel chest tightness with pleuritis?

Patients with pleurisy occasionally experience chest tightness, which is a very common clinical symptom. It is important to clarify that in clinical cases, pleurisy is mostly due to infection of the pleural cavity by Mycobacterium tuberculosis, causing clinical symptoms such as fever, chest tightness, shortness of breath, cough, and chest pain. Therefore, during an acute episode of pleurisy, some patients may have a severe pleural infection, and possibly a large amount of pleural effusion, which inevitably leads to symptoms like shortness of breath and chest tightness. For patients with pleurisy, if it is tuberculous, it is crucial to provide anti-tuberculosis medication as early as possible for symptomatic treatment. A lengthy course of treatment is usually required to effectively control the discomfort caused by pleurisy.

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Written by Liu Jing Jing

Pulmonology

52sec

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Is pleurisy ascites easy to treat?

Whether pleurisy with effusion is easy to treat depends on identifying the cause of the pleurisy, which commonly includes tuberculosis, infection, and tumors. Tuberculous pleurisy can usually be cured about six months to a year after standard anti-tuberculosis treatment; infectious pleurisy generally has a good prognosis if it is sensitive to anti-infective drugs; however, pleurisy caused by tumors often indicates metastasis to the pleura, and at this stage, surgical options are no longer viable, leading to a poor prognosis. Therefore, if pleurisy is present, it is necessary to go to the hospital to complete thoracic puncture and clarify the nature of the pleural effusion, and treat according to the cause.

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Written by An Yong Peng

Pulmonology

58sec

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What are the symptoms of pleurisy?

Pleurisy often presents with symptoms of chest pain, which tends to worsen with deep breathing. Patients with pleurisy may also experience a feeling of tightness in the chest, possibly caused by a significant accumulation of fluid in the chest cavity due to the pleurisy. Sometimes, this tightness could also be due to severe chest pain that makes the patient reluctant to inhale deeply. Patients with pleurisy are likely to exhibit symptoms of fever. It is important to note that pleurisy caused by different factors may have distinct clinical features. For example, purulent pleurisy often presents with high fever, while tuberculous pleurisy may show symptoms of tuberculosis intoxication like low-grade fever in the afternoon and night sweats. However, some cases of tuberculous pleurisy might present with high fever, and others may not have noticeable fever at all. Additionally, viral pleurisy usually features prominently painful symptoms in the chest.

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Written by Wang Chun Mei

Pulmonology

43sec

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Does pleurisy cause chest pain?

Pleurisy can cause anterior chest pain. It is a very common clinical disease, mostly caused by bacterial invasion of the pleura resulting in inflammatory lesions, with Mycobacterium tuberculosis being the most common pathogen. Due to inflammatory exudation, some patients may also experience varying degrees of pleural effusion. The clinical symptoms presented by patients mainly include fever, cough, shortness of breath, chest tightness, and chest pain. In severe cases, different levels of breathing difficulties and other clinical symptoms may occur. Therefore, it is very common for patients with pleurisy to experience anterior chest pain.

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Written by Zhang Zhi Gong

Cardiothoracic Surgery

49sec

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What are the symptoms of pleurisy and pneumothorax?

The pleural cavity in healthy individuals is a potential space and is under negative pressure. Its main purpose is to allow the lungs to fully adhere to the chest wall, and the lubricating fluid present serves to prevent too much friction between the lungs and chest wall during deep inhalation, which could cause pain. For various reasons, such as a ruptured lung bulla or trauma to the chest wall, a certain amount of air can enter the pleural cavity, leading to pain in patients. Due to the presence of pleurisy, friction occurs between the lungs and chest wall—particularly between the lower chest wall and the lungs—causing intense pain during deep inhalations. If a large volume of air is present, it can prevent the lungs from fully expanding, potentially leading to symptoms of breathing difficulties or an obstructed exhalation.