What is the best medicine for bladder cancer infusion?

Written by Liu Mei Fen
Medical Oncology
Updated on September 20, 2024
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Bladder perfusion chemotherapy involves infusing chemotherapy drugs directly into the bladder through a catheter to control tumor growth and reduce the recurrence rate after surgery. Generally, the drugs with significant effects on bladder perfusion fall into three categories. The first category is the anthracyclines, including doxorubicin, epirubicin, and pirarubicin. The second category includes platinum-based drugs such as cisplatin, carboplatin, and oxaliplatin. The third category is vinorelbine. According to current big data research, vinorelbine bladder perfusion tends to have a lower recurrence rate. Without postoperative bladder perfusion chemotherapy, 60%-70% of patients will eventually experience recurrence. With bladder perfusion chemotherapy, the recurrence rate can be reduced to 20%-30%.

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Written by Guan Hai Fang
Urology
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How is bladder cancer diagnosed?

Firstly, imaging examinations such as ultrasound can be conducted, which if reveal tumors larger than 0.5 cm can serve as an initial screening for patients; IVU (Intravenous Urography) can show larger tumors as filling defects. Cystoscopy can also be performed by inserting a cystoscope to directly examine the bladder's shape, size, etc. If it appears round, with clear boundaries and without erosion, it is generally benign; if it has a cauliflower-like or seaweed-like appearance, it is generally malignant bladder cancer. Urine tests can also be conducted; cells from tumors found in fresh urine can lead to cytological examination of urine as an initial screening. Additionally, if conditions permit, a physical examination including a bimanual examination of the bladder can be done to preliminarily assess the tumor's size, the extent of invasion, depth, and its relationship with the pelvic wall.

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Written by Wu Xia
Oncology
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Diet for Bladder Cancer Patients

From the perspective of Western medicine, the diet for bladder cancer patients involves drinking plenty of water, avoiding spicy foods, and abstaining from alcohol and tobacco. Patients should also ensure they get enough vitamins by consuming fresh fruits and vegetables. Additionally, it is important to consume adequate nutrition including eggs, meat, and fish, and patients should not hold in urine. However, from the perspective of Chinese medicine, bladder cancer patients should avoid foods that induce excessive internal heat, such as lamb and seafood, and should also avoid cold or chilled foods.

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Written by Liu Liang
Oncology
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Does bladder cancer require the removal of the bladder?

Whether or not to remove the entire bladder in cases of bladder cancer depends on whether the tumor has invaded the base layer and whether there is distant metastasis. For non-muscle invasive bladder cancer, where the muscle layer is not invaded and there is no distant metastasis, typically found in stage 0 and stage 1 bladder cancer patients, there is no need for complete removal of the bladder. The standard treatment in such cases generally involves transurethral resection of the bladder tumor. If the tumor has invaded the base layer but there is no distant metastasis, termed muscle-invasive bladder cancer, patients in this category require radical cystectomy, which involves the removal of the entire bladder. If there is distant metastasis, termed metastatic bladder cancer, surgical treatment is not pursued; instead, palliative chemotherapy is the primary approach.

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Written by Liu Mei Fen
Medical Oncology
1min 4sec home-news-image

What is the best medicine for bladder cancer infusion?

Bladder perfusion chemotherapy involves infusing chemotherapy drugs directly into the bladder through a catheter to control tumor growth and reduce the recurrence rate after surgery. Generally, the drugs with significant effects on bladder perfusion fall into three categories. The first category is the anthracyclines, including doxorubicin, epirubicin, and pirarubicin. The second category includes platinum-based drugs such as cisplatin, carboplatin, and oxaliplatin. The third category is vinorelbine. According to current big data research, vinorelbine bladder perfusion tends to have a lower recurrence rate. Without postoperative bladder perfusion chemotherapy, 60%-70% of patients will eventually experience recurrence. With bladder perfusion chemotherapy, the recurrence rate can be reduced to 20%-30%.

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Written by Wang Jian
Urology
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Is bladder cancer scary?

Bladder cancer is the most common malignant tumor in urological surgery, primarily occurring in the bladder mucosa. Its symptoms include painless, intermittent gross hematuria, with nearly 100% of patients experiencing blood in the urine. The presence of hematuria should highly raise the suspicion of bladder cancer, and the examinations mainly include routine urinalysis and an ultrasound of the urinary system. Bladder cancer is not to be feared if it is detected and treated early. The surgery can be relatively simple, and minimally invasive treatment through the urethra, such as plasma electrosection or laser excision, is possible. Since bladder cancer can recur, postoperative management should include bladder perfusion therapy and regular cystoscopy re-examinations. Thus, bladder cancer is not to be feared, as early detection and treatment can lead to a cure.