What medicine is infused into the bladder for bladder cancer?

Written by Liu Liang

Oncology

Updated on September 10, 2024

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Postoperative intravesical chemotherapy infusion is very common in the treatment of bladder cancer. Common drugs used for infusion chemotherapy include mitomycin and anthracyclines such as epirubicin or pirarubicin. Gemcitabine is also frequently used for this purpose. The related side effects generally include irritation symptoms of the bladder, although some patients may experience relatively mild side effects.

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Written by Wang Jian

Urology

52sec

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Is bladder cancer scary?

Bladder cancer is the most common malignant tumor in urological surgery, primarily occurring in the bladder mucosa. Its symptoms include painless, intermittent gross hematuria, with nearly 100% of patients experiencing blood in the urine. The presence of hematuria should highly raise the suspicion of bladder cancer, and the examinations mainly include routine urinalysis and an ultrasound of the urinary system. Bladder cancer is not to be feared if it is detected and treated early. The surgery can be relatively simple, and minimally invasive treatment through the urethra, such as plasma electrosection or laser excision, is possible. Since bladder cancer can recur, postoperative management should include bladder perfusion therapy and regular cystoscopy re-examinations. Thus, bladder cancer is not to be feared, as early detection and treatment can lead to a cure.

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Written by Liu Mei Fen

Medical Oncology

1min 4sec

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What is the best medicine for bladder cancer infusion?

Bladder perfusion chemotherapy involves infusing chemotherapy drugs directly into the bladder through a catheter to control tumor growth and reduce the recurrence rate after surgery. Generally, the drugs with significant effects on bladder perfusion fall into three categories. The first category is the anthracyclines, including doxorubicin, epirubicin, and pirarubicin. The second category includes platinum-based drugs such as cisplatin, carboplatin, and oxaliplatin. The third category is vinorelbine. According to current big data research, vinorelbine bladder perfusion tends to have a lower recurrence rate. Without postoperative bladder perfusion chemotherapy, 60%-70% of patients will eventually experience recurrence. With bladder perfusion chemotherapy, the recurrence rate can be reduced to 20%-30%.

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Written by Zou De Bo

Urology

29sec

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How to prevent bladder cancer

Bladder cancer is one of the most common malignant tumors in the urinary system. Currently, the exact cause of bladder cancer is not clear. In terms of prevention, it is generally necessary to drink more water, urinate more frequently, try not to smoke, and reduce exposure to chemical irritants, such as paint, chemical substances, etc. Additionally, an annual physical examination is recommended to enable early detection and early treatment.

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Written by Xu Chun Hua

Urology

39sec

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Early symptoms of bladder cancer

Hematuria is the most common and earliest symptom of bladder cancer, with 85% of patients experiencing intermittent gross hematuria which can decrease or stop on its own, often giving patients a false impression of improvement or cure, thus delaying treatment. Sometimes, hematuria is also found under a microscope, and the amount of bleeding is not necessarily consistent with the size, number, or malignancy of the tumor. The hematuria from bladder tumors can initially be mild, and other symptoms such as frequent urination, urgency, and painful urination may also occur; these are all manifestations of bladder tumors.

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Written by Wang Jian

Urology

57sec

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Treatment of bladder cancer

For the treatment of bladder cancer, it is necessary first to confirm the diagnosis of bladder cancer through routine urine tests, ultrasonographic examination of the urinary system, cystoscopy, and imaging studies of the urinary system. It is important to determine the location, area, and malignancy of the bladder tumor. For early-stage superficial bladder tumors or tumors on the bladder wall with fewer numbers, minimally invasive surgery can be performed, followed by bladder perfusion to prevent recurrence of the bladder tumor. In the second scenario, if the bladder tumor is multiple and larger, and has a higher degree of malignancy in the bladder trigone area, then a radical cystectomy is required. Radical cystectomy involves the removal of the bladder along with the prostate in males or the uterus in females, followed by the creation of a urinary diversion, typically through these two treatment methods.