In the treatment of amenorrhea, systemic treatment plays an important role. It includes active treatment of systemic diseases, improving the overall quality of the body, and then providing adequate nutrition to maintain standard weight. In cases of exercise-induced amenorrhea, it is appropriate to reduce the amount of exercise. For amenorrhea caused by stress and psychological reasons, patient psychological therapy should be conducted to eliminate mental tension and anxiety. If the amenorrhea is caused by pathological conditions like tumors or polycystic ovary syndrome, then etiological treatment should be given. Once the cause of the disease is identified, appropriate hormonal treatment should be provided to supplement insufficient hormones in the body and counteract excess, aiming to regulate and treat amenorrhea.