How long does breast cancer metastasis take?

Written by Zhang Chao Jie
Breast Surgery
Updated on December 09, 2024
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How long does it take for breast cancer to metastasize? There is no absolute scientific data on this issue. Based on data from theoretical animal experiments, metastasis can occur within a few hours, tens of hours, several days, or even years. It should be understood in this way. I believe your question primarily concerns how long after breast cancer surgery metastasis might typically occur. Generally speaking, after comprehensive treatments such as surgery, chemotherapy, and endocrine therapy, the earliest metastases appear within a year. The peak incidence for most people is between two to three years after treatment, making this period critical for frequent check-ups. During the first two years, stringent, thorough examinations every three months are essential. After two years, check-ups every six months continue from the third to the fifth year. After five years, annual physical examinations are recommended. A second peak period for recurrence occurs around eight to nine years post-surgery, which is why the frequency of examinations increases again during this time.

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Early manifestations of breast cancer

Early-stage breast cancer is primarily characterized by a single, painless small lump, which is hard with unclear boundaries and a rough surface, blending indistinguishably with surrounding tissues and difficult to move within the breast. It is usually discovered accidentally or while bathing. Swollen lymph nodes may be present, and the nipple may be inverted with possible bloody discharge. As the tumor grows, it may invade the Cooper's ligaments, causing the skin to dimple, a condition known as peau d'orange. These are all early symptoms of breast cancer. If the condition progresses, it may lead to a skin texture resembling orange peel.

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Breast cancer symptoms

The symptoms of breast cancer depend on the severity of the cancer and whether there are any signs of metastasis or recurrence. It is important to emphasize that over 90% of breast cancer cases do not involve pain as a symptom. This means that the earliest symptoms of breast cancer are usually determined by whether the cancer is in its early or late stages. Early-stage breast cancer may have no symptoms at all, or there may be signs such as a lump or hard nodule in the breast, discharge from the nipple, especially coffee-colored or bloody discharge. Late-stage symptoms can include changes in the skin of the breast resembling the texture of an orange peel, palpable large lymph nodes in the armpit that are hard but neither painful nor itchy. If the cancer has metastasized to the lungs, chest cavity, pleura, liver, bones, or head, symptoms might include chest pain, coughing, difficulty breathing, abdominal distention, bone pain or fractures, as well as headaches, eye pressure, and dizziness, among others. Therefore, the symptoms of breast disease depend on whether the cancer is in its early stages; if it is in a late stage and has metastasized to other parts, corresponding symptoms will be present. It is also important to remember that early-stage breast cancer may not show any symptoms at all.

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Symptoms of male breast cancer

The clinical symptoms of male breast cancer are generally similar to those of females, mainly presenting as painless, progressive enlargement of breast lumps. These breast lumps usually occur under the areola, and some patients may experience nipple inversion or abnormal nipple discharge. Many breast lumps tend to have unclear boundaries with surrounding tissues and often adhere to the skin or chest muscles. Many patients with male breast cancer experience metastasis to the axillary lymph nodes, causing the metastatic lymph nodes to enlarge and become painful, local lymphatic drainage obstruction, and causing local upper limb swelling and pain. Moreover, some male breast cancer cases have metastasized to the lungs, presenting clinically with symptoms such as coughing and chest pain related to the respiratory system. Some patients with male breast cancer have liver metastasis, clinically presenting with pain in the liver area, decreased appetite, and abnormal coagulation functions.

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Causes of Breast Cancer

The causes of breast cancer are not yet fully understood, but research has shown that the onset of breast cancer follows certain patterns and is related to various risk factors: The first is the age of onset for female breast cancer, which is generally low from ages zero to twenty-four, gradually increases after twenty-five, and peaks from fifty to fifty-four years old. So, the first factor is related to age; The second factor is genetics. If a mother or sister has breast cancer, then the individual’s likelihood of developing breast cancer may be higher, making family history a relevant factor; The third point involves risk factors related to the breast, including early menarche (before the age of twelve), late menopause (after the age of fifty-five), being unmarried, nulliparous, late marriage, and not breastfeeding. These factors also tend to increase the likelihood of developing breast cancer; The fourth point is that benign breast conditions, if not promptly diagnosed and treated, could potentially transform into malignant tumors; The fifth point includes potential exposure to radiation, long-term use of exogenous estrogens, postmenopausal obesity, chronic alcohol consumption, and an irregular lifestyle, all of which can also have an impact.

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How does one get breast cancer?

How is breast cancer caused? Regarding the causes of breast cancer, the primary factor should be family history. If a first-degree relative has breast cancer, then the likelihood of developing breast cancer increases. The second factor is reproductive factors; for instance, if the age at menarche is quite young, menopause age is relatively late, menstrual cycles are short, there is no childbirth or the age at first full-term pregnancy is older, there are fewer childbirths, and there is a lack of breastfeeding, then the incidence of breast cancer is also higher. The third factor involves hormones, possibly related to endogenous hormones or exogenous hormones, such as those mainly associated with oral contraceptives used externally. The fourth major point is a high-fat diet, or habits like drinking alcohol, smoking, and a diet low in vitamins, which may increase the risk of breast cancer. The fifth point involves other factors, such as exposure to significant amounts of ionizing radiation, chemicals from cancer drugs, lack of physical exercise, and occupations, such as working in the beauty industry or pharmaceutical manufacturing, etc., which may also increase the chances of developing breast cancer.