Chronic urticaria is relatively difficult to cure completely. It can be managed effectively through standardized medication and lifestyle adjustments to reduce the frequency of outbreaks. Chronic urticaria is usually related to a decrease in the body's immunity; certain allergens can also trigger it. Therefore, treatment of chronic urticaria should include medications that enhance immune function combined with antihistamines. Commonly used thymopeptides can strengthen immunity, and antihistamines such as chlorcyclizine hydrochloride tablets, olopatadine hydrochloride tablets, or loratadine tablets may be chosen. It is also important to avoid inhaling, touching, or ingesting substances that trigger urticaria. Additionally, avoiding staying up late, maintaining a regular schedule, avoiding spicy and irritating foods, and engaging in appropriate exercise to enhance the body's immunity are recommended.