Medications for treating gastric ulcers

Written by Wang Hui Jie
Gastroenterology
Updated on September 20, 2024
00:00
00:00

Here I will introduce several major types of medications for treating gastric ulcers, but specific medication use should be consulted with a doctor or pharmacist according to individual conditions. The first major type is anti-gastric acid medications. Since gastric acid plays a significant role in ulcerative lesions, it is considered appropriate to treat gastric ulcers by adjusting the stomach environment to a pH of 3.5. Anti-acid medications include antacids, H2 receptor antagonists, proton pump inhibitors, and others. The second major type is gastric mucosal protectants, which include some class B drugs, prostaglandin derivatives, and some containing sucralfate. The third major type is medications that treat Helicobacter pylori, with quadruple therapy currently being a common practice. Note: Medications should be used under the guidance of a doctor.

Other Voices

doctor image
home-news-image
Written by Li Xue Qing
Gastroenterology
1min 36sec home-news-image

How to treat gastric ulcers?

The treatment of gastric ulcers mainly consists of general management and pharmacotherapy. General management involves patients avoiding spicy, stimulating, and cold foods, eating regular meals, and avoiding medications that may harm the stomach, such as non-steroidal anti-inflammatory drugs. Pharmacotherapy mainly includes gastroprotective therapy and treatment against Helicobacter pylori. Gastroprotective therapy includes neutralizing stomach acid with agents such as magnesium carbonate chewing tablets, acid-suppressing medications like proton pump inhibitors and H2 receptor antagonists, pantoprazole, cimetidine, etc. Medications to protect the gastric mucosa, such as sucralfate, bismuth preparations, etc., are also used. Treatment against Helicobacter pylori mainly includes triple and quadruple therapy. Triple therapy involves a proton pump inhibitor or a bismuth agent combined with two types of antibiotics, and quadruple therapy consists of a proton pump inhibitor, a bismuth agent, and two types of antibiotics. Antibiotics commonly used include amoxicillin, clarithromycin, furazolidone, levofloxacin, metronidazole, tetracycline, etc. Treatment generally lasts seven to ten days, with overall therapy for gastric ulcers spanning about a month. (Please undertake any medication under the guidance of a doctor.)

doctor image
home-news-image
Written by Jiang Guo Ming
Gastroenterology
48sec home-news-image

What to eat for nutrition when suffering from bleeding gastric ulcers?

This condition should be a benign gastric ulcer with bleeding, during the recovery period after treatment. In addition to adhering to medical advice and maintaining medication, daily living habits are especially important. The stomach needs care; firstly, it is essential to quit smoking and drinking, avoid getting cold, and one can engage in appropriate activity, but avoid strenuous sports. Regarding diet, it should consist of light, easily digestible foods, such as soft rice, noodles, and porridge, among others. In particular, various fresh vegetables and fruits should be chosen. Try to avoid consuming too much raw, greasy, spicy foods, and alcoholic beverages. Patients with gastric ulcers need to have regular check-ups, and it's also important to maintain a positive mindset.

doctor image
home-news-image
Written by Li Xue Qing
Gastroenterology
1min home-news-image

Complications of gastric ulcers

The main complications of gastric ulcers are fourfold: one is upper gastrointestinal bleeding; the second is perforation; the third is pyloric obstruction; the fourth is malignant transformation. Upper gastrointestinal bleeding is the most common complication of gastric ulcers. If a patient has experienced bleeding, there is a high likelihood of recurrence. Perforations mainly occur in elderly individuals. Pyloric obstruction is primarily caused by ulcers in the pyloric canal and pre-pyloric area. It is divided into mechanical obstruction and functional obstruction. Mechanical obstruction results from scarring after the ulcer heals, which narrows the pyloric opening. Functional obstruction is due to congestion and edema of the mucosa after the ulcer, causing relative narrowing of the pylorus. As for malignant transformation, it is still controversial, but it is generally believed to be around 1%-7%.

doctor image
home-news-image
Written by Jiang Guo Ming
Gastroenterology
45sec home-news-image

Can gastric ulcers be cured?

Gastric ulcers are classified into benign and malignant types. Most duodenal bulb ulcers and gastric ulcers are benign and can be cured through medication. Treatment plans are usually determined based on the presence of Helicobacter pylori infection. Patients with Helicobacter pylori infection can be treated with antibacterial therapy. If there is no infection, symptomatic treatment alone is generally sufficient for a cure. If the ulcer is malignant or is a giant ulcer, surgical treatment is generally required. For those who cannot undergo surgery, radiotherapy or chemotherapy may be needed. Generally, the prognosis for malignant ulcers is worse than for benign ulcers.

doctor image
home-news-image
Written by Ren Zheng Xin
Gastroenterology
42sec home-news-image

Early symptoms of gastric ulcer

Gastric ulcers refer to ulcerative lesions on the gastric mucosa and are very common in gastroenterology. Typical symptoms include pain in the upper abdomen, often presenting as dull pain or a burning sensation in the early stages. Particularly after eating, pain in the upper abdomen occurs within an hour and gradually eases after two hours. As the condition progresses, complications such as gastric bleeding and gastric perforation may occur. Diagnosis can be confirmed clinically through a barium meal examination and gastroscopy. Currently, with the development of internal medicine drugs, most gastric ulcers can be treated with medication.