Medications for treating gastric ulcers

Written by Wang Hui Jie
Gastroenterology
Updated on September 20, 2024
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Here I will introduce several major types of medications for treating gastric ulcers, but specific medication use should be consulted with a doctor or pharmacist according to individual conditions. The first major type is anti-gastric acid medications. Since gastric acid plays a significant role in ulcerative lesions, it is considered appropriate to treat gastric ulcers by adjusting the stomach environment to a pH of 3.5. Anti-acid medications include antacids, H2 receptor antagonists, proton pump inhibitors, and others. The second major type is gastric mucosal protectants, which include some class B drugs, prostaglandin derivatives, and some containing sucralfate. The third major type is medications that treat Helicobacter pylori, with quadruple therapy currently being a common practice. Note: Medications should be used under the guidance of a doctor.

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What should not be eaten with gastric ulcers?

Patients with gastric ulcers should be cautious about their diet, abstain from smoking and alcohol, and avoid drinking strong tea, coffee, eating fatty, greasy, spicy, fried, barbecued, raw, cold, and sweet foods, as well as drinking milk and soy milk, or eating glutinous rice and sweet potatoes. This is because some of these foods can stimulate the secretion of gastric acid, worsening the irritation of gastric mucosa and exacerbating gastric ulcers. Some are difficult to digest, thus, they are not recommended. It is advisable to eat porridge, drink soups, eat noodles, such as millet porridge, yam porridge, barley porridge, chicken soup, and pork rib soup. When eating meats, ensure they are well-stewed before consumption.

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Does gastric ulcer require hospitalization?

Whether a stomach ulcer requires hospitalization depends on the condition. For minor ulcers, if the pain is mild and there are no significant symptoms of vomiting or nausea, treatment can be managed with medication, such as drugs that inhibit stomach acid secretion and protect the gastric mucosa. It is also important to regulate diet, eat soft foods, avoid cold, spicy foods, and alcohol, as symptoms can gradually ease. If the ulcer is larger and exhibits perforation or bleeding, hospital treatment is necessary, usually involving a significant portion of the stomach being surgically removed to completely cure the ulcer. (Medication should be taken under the guidance of a doctor.)

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Can you smoke with a stomach ulcer?

Patients with gastric ulcers should not smoke, as the tar and nicotine in tobacco can damage the gastric mucosa and worsen ulcer symptoms. Patients should pay attention to proper rest, reduce mental stress, avoid excessive tension and irritability, develop regular living habits, eat meals at fixed times and in fixed amounts, eat more vegetables and fruits, eat less spicy and greasy food, and avoid smoking and drinking alcohol. It's also important to consume less strong tea and coffee. Actively use medications for treatment, commonly including drugs that inhibit gastric acid secretion and drugs that protect the gastric mucosa. If there is Helicobacter pylori infection, it is necessary to eradicate Helicobacter pylori. (Medications should be used under the guidance of a doctor.)

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How is a gastric ulcer diagnosed?

Gastric ulcers are inflammatory defects that occur on the gastric mucosa, related to the gastric acid and digestive actions of gastric juices. Diagnosis mainly relies on clinical manifestations and auxiliary examinations, with typical symptoms including recurring or periodic upper abdominal pain that worsens after eating, as well as occurrences of belching. X-ray barium meal examinations can reveal filling defects, and gastroscopy can provide a full view of the ulcer. Treatment primarily involves the use of medications that suppress gastric acid secretion and protect the gastric mucosa. Additionally, it is important to enhance health education, eat less spicy and greasy food, have meals regularly and in measured amounts, and consume more green vegetables. (Specific medication use should be carried out under the guidance of a doctor.)

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How long does it take for a stomach ulcer to heal?

Gastric ulcers are a very common disease in gastroenterology. For minor ulcers, adjustments in diet, quitting smoking and drinking, consuming more green vegetables, getting more rest, and reducing mental stress can gradually lead to recovery. More severe ulcers require active medication use. To achieve ulcer healing, the course of acid-reducing medication usually lasts four to six weeks. Commonly used medications include those that inhibit gastric acid secretion, such as HR receptor antagonists and proton pump inhibitors, as well as some bismuth agents and weakly alkaline antacids to protect the stomach lining. Meanwhile, dietary management should be strengthened. Through effective medical treatment, the healing rate of gastric ulcers can reach over 95%. (Specific medication use should be conducted under the guidance of a doctor.)