Causes of Arteriosclerosis

Written by Zeng Wei Jie
Cardiology
Updated on September 16, 2024
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Arteriosclerosis, the most common and important type of arteriosclerosis, is characterized by thickening and hardening of the arterial walls, loss of elasticity, and narrowing of the lumen. The causes are currently considered to be related to several factors, including age and gender, with older males being more prone. Patients with abnormal blood lipids, hypertension, smokers, those with diabetes or impaired glucose tolerance, obese patients, and those with a family history are all more likely to develop arteriosclerosis. Due to the incomplete certainty of the causes, its prevention and control are also managed through multiple factors.

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The difference between arteriosclerosis and atherosclerosis

Arteriosclerosis is a common and important type among a group of vascular diseases known as arteriosclerosis. The common characteristics of various arterioscleroses include thickening and hardening of arterial walls, loss of elasticity, and narrowing of the lumen. Atherosclerosis is a type of arteriosclerosis characterized by lesions starting from the arterial intima, subsequently involving the accumulation of lipids and complex carbohydrates, bleeding, thrombosis, proliferation of fibrous tissues, and deposition of calcium, along with gradual degeneration and calcification of the arterial media. Since the lipids accumulated in the arterial intima appear yellowish and mushy, it is termed atherosclerosis.

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Can arteriosclerosis be cured?

Atherosclerosis can only slow down its further progression and prevent the further occurrence of conditions such as coronary heart disease, cerebral infarction, and lower limb arterial occlusion. This is because it is influenced by many factors, including both modifiable and non-modifiable risk factors. For example, modifiable factors include abnormal blood lipids, hypertension, diabetes, smoking, and overweight obesity, which we can change. However, there are also non-modifiable factors such as age, genetics, and environmental factors. As age increases, the incidence of atherosclerosis significantly rises. Its pathological changes generally begin in childhood or adolescence, with symptoms becoming more apparent as age progresses.

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Can arteriosclerosis be treated with moxibustion?

Arteriosclerosis can be treated with moxibustion. Moxibustion is a traditional disease treatment method in Chinese medicine, which can treat many diseases clinically. For patients with arteriosclerosis, moxibustion therapy can improve some clinical symptoms caused by arteriosclerosis. However, one should not rely solely on moxibustion for the treatment of atherosclerosis, as the mechanism of atherosclerosis is due to the disorder of lipid metabolism and the hardening of arterial walls caused by increased blood lipids. Treatment should include medication and dietary adjustments such as low-salt, low-sugar, and low-fat diets, and avoiding fatty meats, animal offal, and seafood high in cholesterol.

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What tests are used for arteriosclerosis?

If arteriosclerosis is in the early stages, we need to understand the situation with lipids and blood sugar, so lipid and blood glucose tests should be done. Later on, when some atheromatous plaques appear, examinations such as color Doppler ultrasound and cardiac echocardiography can be done to assess blood flow and the degree of narrowing in the vessels. For some severe narrowings, consider conducting a CTA, MRI, or angiography, which can non-invasively understand the lesions of arteriosclerosis. For some patients, if there is a need for interventional treatment, invasive, selective arterial angiography can be performed to understand the condition of the lesions. Therefore, different tests can be chosen at different stages.

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The earliest lesions of arteriosclerosis

The earliest lesion of atherosclerosis is the formation of lipid spots and streaks. The so-called lipid spots are small yellow dots that appear on the arterial intima. Under pathological observation, these are small areas of macrophages containing lipid droplets, forming a cluster of foam cells. As this small yellow dot develops, it gradually turns into a yellow streak made up of layers of macrophages containing lipids. The intima also comprises smooth muscle cells and lipids, as well as an infiltration of T cells, resembling a yellow streak on the intima.