Kidney cancer

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Written by Xu Chun Hua
Urology
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kidney cancer immunotherapy drugs

The immunotherapy for kidney cancer often involves the use of interferons or interleukins, and the results are generally satisfactory. The effects of radiotherapy and chemotherapy for kidney cancer are not very certain. Typically, after kidney cancer is diagnosed, radical nephrectomy is performed. During the surgery, adequate exposure is essential. The renal hilum should be ligated first to prevent cancer cells from being squeezed into the bloodstream during surgery. It is also necessary to remove the fascia and fat around the kidney, along with the lymph nodes at the renal hilum. Combining these surgical measures with immunotherapy usually yields very ideal results.

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Written by Xu Chun Hua
Urology
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What tests are done to diagnose kidney cancer?

The typical clinical manifestations of renal cancer are hematuria, a mass, and flank pain, but these symptoms generally appear only in the middle and late stages. CT scans often play a decisive role in the diagnosis of renal cancer. Ultrasound examinations are mainly used to screen for the presence of tumors in the entire urinary system, while excretory urography can reveal compression inside the renal pelvis by the tumor, which may show irregular deformations, narrowing, or elongation. Generally speaking, CT scans are quite important for the diagnosis of renal cancer and also play a decisive role.

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Written by Xu Chun Hua
Urology
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Can you have sexual intercourse after kidney cancer removal?

After kidney cancer removal, based on an individual's physical condition, sexual activity can still be undertaken. Radical nephrectomy is also the best treatment method. During the surgery, it is often necessary to fully expose the area, first ligating the renal pedicle to prevent squeezing cancer cells into the bloodstream during surgery, while also removing the fascia and fat around the kidney, along with the lymph nodes at the hilum. After the surgery, it is also necessary to complement this with immunotherapy, such as using interferons and interleukins for immune treatment. Patients with kidney cancer can engage in appropriate sexual activities after surgery, but they should not be too strenuous, aiming not to feel tired the following day.

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Written by Zou De Bo
Urology
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Kidney cancer thrombus

Tumor thrombus is one of the common complications of tumors, and refers to cancer cells in blood vessels or lymphatic vessels similar to blood clots, i.e., cancer cells clustering together, invading the vessels, and causing abnormalities in blood coagulation function, leading to disorders in blood circulation and abnormal coagulation with clustered cancer cells. Generally, the risk of tumor thrombus formation is very high, and patients with tumor thrombus have much worse treatment outcomes than those without. Renal cancer is also a tumor commonly associated with tumor thrombus. Once a tumor thrombus occurs, it indicates that the surgery might be staged quite late, and thus, its treatment results are also relatively poor.

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Written by Zou De Bo
Urology
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Difference between Renal Cancer and Renal Pelvis Cancer

First, the sites of the disease are different; renal pelvis cancer usually occurs in the epithelium of the renal pelvis or calyces, while renal cancer typically originates from the epithelial cells of the renal tubules. Second, the presentations are different; hematuria is a common symptom of both renal pelvis cancer and renal cancer. However, in renal pelvis cancer, hematuria can occur early, while in renal cancer, hematuria may not be seen until the tumor has invaded the renal pelvis or calyces. Third, the diagnostic tests are different; the clinical diagnosis of renal cancer heavily relies on CT scans, whereas renal pelvis cancer primarily depends on excretory or retrograde urography, that is, CT urography. Fourth, the CT appearances are different; on CT scans, renal cancer typically shows as a multicystic lesion with more pronounced enhancement during contrast than that seen in renal pelvis cancer. Fifth, the results of cytological examinations are different; cytology of renal pelvis cancer may show positive tumor cells, but renal cancer might test negative.

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Written by Zou De Bo
Urology
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early symptoms of kidney cancer

Early symptoms may include hematuria, which is often painless, intermittent, and visible throughout. Hematuria caused by renal cancer is often due to blood clots blocking the fallopian tubes, and the clots can form stripes through the ureter. Secondly, back pain may occur, which is another common symptom of kidney cancer. It is mostly dull pain felt in the back and may be caused by the growth of the tumor. Thirdly, a mass may appear, which can be felt in the abdomen during a medical examination. Generally, feeling a mass in the abdomen is possibly a symptom of the advanced stage.

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Written by Zou De Bo
Urology
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The typical three major symptoms of kidney cancer

The typical three major symptoms of kidney cancer are hematuria, pain, and a mass. If these three symptoms appear, it generally indicates that the condition has reached an advanced stage, at which point the patient may have missed the optimal timing for treatment. Surgery at this stage may also be challenging to perform completely. Therefore, early detection and treatment are essential. The five-year survival rate after kidney cancer surgery is as high as 97% for many people. Thus, overall, the prognosis for kidney cancer is relatively good. However, the best treatment approach remains surgery, including nephron-sparing surgery and radical nephrectomy, depending on the size of the tumor. Generally, for tumors smaller than four centimeters, nephron-sparing treatment can be adopted.

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Written by Xu Chun Hua
Urology
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How is kidney cancer diagnosed?

Hematuria, pain, and lumps are the main symptoms of kidney cancer. If one or two of these symptoms appear, the possibility of kidney cancer should be considered. About half of the patients are found to have incidental kidney cancers, also known as asymptomatic kidney cancers, during physical examinations through incidental findings on ultrasound or CT scans. Some may show early symptoms of metastasis making the diagnosis quite challenging. The preoperative diagnosis of kidney cancer relies on the results of medical imaging examinations such as ultrasound, X-rays, and CT scans. CT scans have a very high confirmation rate for kidney cancer and are currently the most reliable imaging method for diagnosing kidney cancer.

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Written by Zou De Bo
Urology
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What are the characteristic symptoms of kidney cancer?

Most kidney cancer patients are discovered during health check-ups, and these patients may account for over 50%-60% of all kidney cancer cases. Among those with symptoms, the most common symptoms are lower back pain and blood in urine. A few patients also present with abdominal masses. 10%-40% of patients can exhibit paraneoplastic syndromes, manifested as high blood pressure, anemia, weight loss, cachexia, fever, abnormal liver function, hyperglycemia, increased erythrocyte sedimentation rate, and other changes. Additionally, symptoms such as bone pain, fractures, cough, and coughing blood can occur due to tumor metastasis.

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Written by Wang Jian
Urology
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Is stage II kidney cancer considered early stage?

The staging of kidney cancer is primarily based on the size of the tumor, whether there is lymph node metastasis, involvement of adjacent organs or lymphatic vessels, and metastasis to distant organs. The TNM staging system is commonly used in clinical settings to stage kidney cancer, where "T" represents the depth of tumor invasion, "N" represents the status of lymph node metastasis, and "M" represents distant metastasis. Stage II refers to a tumor with a maximum diameter greater than seven centimeters but confined to the kidney. Stage II is further divided into stage IIA and stage IIB. Stage IIA refers to a tumor with a maximum diameter greater than seven centimeters but less than ten centimeters, confined to the kidney. Stage IIB refers to a tumor with a maximum diameter greater than ten centimeters, but still confined to the kidney. In the case of stage II kidney cancer, although it is an early stage, curative treatment can be achieved through surgery. Therefore, if diagnosed with stage II kidney cancer, it is vital to pursue aggressive treatment.