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Encephalitis
Pediatric Encephalitis Examination Items
Encephalitis in children is primarily due to a lowered immune resistance, which leads to infection by certain viruses. These viruses invade the nervous system, causing damage to neurons, resulting in symptoms such as fever, headache, nausea, and vomiting. Generally, the main tests for pediatric encephalitis include hematological tests related to bleeding, primarily involving routine blood tests, C-reactive protein, and erythrocyte sedimentation rate. These indices can reflect the inflammatory conditions inside the patient's body, helping to distinguish between viral and bacterial infections. Another very important auxiliary examination is the electroencephalogram (EEG), where pediatric encephalitis can show mild to moderate abnormalities, which is helpful for accurate diagnosis. The third examination involves performing a lumbar puncture to test the cerebrospinal fluid (CSF) for the levels of white cells, glucose, and chloride, which are crucial for diagnosing encephalitis and differentiating it from other types of encephalitis.
Encephalitis belongs to which department?
Encephalitis is primarily a neurological disorder and is an infectious disease of the central nervous system, mainly diagnosed and treated in neurology. There are many causes of encephalitis, with viral encephalitis being the most common. For example, herpes simplex encephalitis is a typical type seen clinically. Patients may experience fever, even with very high temperatures exceeding 40°C, headaches, nausea, and vomiting. If the condition worsens, seizures, coma, and cognitive impairment may occur. These clinical manifestations require further investigations like electroencephalography, cranial MRI, and lumbar puncture. Additionally, there is a specific type of epidemic, known as Japanese encephalitis, which falls under the category of infectious diseases due to its contagious nature.
What tests are conducted for encephalitis?
First, it is generally necessary to conduct an EEG test. This test is very convenient and non-invasive for patients. If significant slow waves are detected, encephalitis cannot be ruled out. Secondly, an MRI of the brain should be performed. If the viral encephalitis is severe, abnormal signals can be observed in areas such as the frontal lobe, temporal lobe, and hippocampus on the MRI, which are of great diagnostic reference value. Thirdly, lumbar puncture is also very important. It allows for a direct observation of the color of the cerebrospinal fluid, to monitor the pressure of the brain fluid, and to test the cerebrospinal fluid for cell count, protein, sugar, and chloride levels. These tests are very important for the diagnosis and differential diagnosis of encephalitis.
After-effects of encephalitis
Some more serious types of encephalitis may leave sequelae. For example, common ones like herpes simplex viral encephalitis and epidemic encephalitis B. A minority of patients may suffer from certain degrees of sequelae, which typically include the following aspects. Firstly, some patients may experience secondary epileptic seizures, which present with loss of consciousness, limb convulsions, incontinence, and frothing at the mouth. These symptoms might require long-term oral medication for epilepsy. Secondly, another consequence of encephalitis is cognitive impairment in patients, characterized by significant reductions in computational ability, memory, and executive function. Additionally, some forms of encephalitis might leave patients with psychiatric symptoms, such as speaking incoherently.
Can encephalitis recur?
Encephalitis comes in various types, some of which are prone to recurrence, while others are monophasic and do not recur. The most common type is viral encephalitis, particularly infections caused by the herpes simplex virus. Although recovery from viral encephalitis after antiviral treatment is possible, it may leave some sequelae, but generally does not recur. Tuberculous meningoencephalitis, however, has a higher rate of recurrence, often related to the resistance of tuberculosis bacteria and inadequate anti-tuberculosis treatment. Patients need repeated lumbar puncture tests to confirm that the cerebrospinal fluid has returned to normal levels and require long-term use of anti-tuberculosis medications. Bacterial meningitis generally does not recur. Additionally, there are some autoimmune types of encephalitis, such as autoimmune encephalitis, multiple sclerosis, and neuromyelitis optica, where recurrence is possible when involving the brain.
What to do with pediatric encephalitis
If a child develops encephalitis, it is definitely recommended that they be hospitalized for treatment. It is necessary to assess their condition and determine the cause of the encephalitis: is it viral? Bacterial? Or caused by other pathogens? If encephalitis occurs, aggressive treatment is certainly required. In such cases, if the child is discharged from the hospital, they must regularly revisit the hospital for follow-up examinations, and the development of the child's nervous system must be monitored, focusing on motor and cognitive development. Regular assessments at the hospital are definitely required.
Symptoms of baby encephalitis
Generally speaking, the symptoms of encephalitis in babies usually start with fever. Encephalitis is an infectious disease, and the majority of cases present with fever, which could be either high or low. Next is vomiting. Since small infants cannot express headache, they usually manifest symptoms through crying, irritability, and restlessness. Additionally, there might be lethargy and malaise. Some may experience seizures, and others might have stiff neck, characterized by rigidity of the neck and changes in muscle tone of the limbs, among other symptoms. These are all symptoms of encephalitis.
How is encephalitis transmitted?
The commonly mentioned encephalitis is mainly caused by viral infections. There are many types of viruses that can cause encephalitis, including the more severe herpes simplex virus, varicella-zoster virus, etc. There are also some enteroviruses, like Coxsackie virus, and some adenoviruses. Typically, the transmission of encephalitis can occur via the fecal-oral route, where some enteroviruses enter the digestive tract through this route, then from the cells of the digestive tract to the bloodstream, and from there to the brain. Additionally, some viruses are transmitted through blood contact. For instance, if a patient has blisters that rupture and release a large amount of virus, and another person's blood comes into contact with these fluids, transmission can occur via blood. Generally, encephalitis is primarily transmitted through fecal-oral routes and bloodborne transmission.
Does encephalitis require hospitalization?
The severity of encephalitis can vary greatly; it is generally caused by viral infection. Among these viruses, Herpes Simplex Virus (HSV) is particularly dangerous. Encephalitis caused by HSV can be very severe, with symptoms including high fever, headache, nausea, vomiting, and other serious manifestations. Some patients may even experience seizures, coma, cognitive decline, and changes in mood and behavior. This type of encephalitis is very severe and definitely requires hospitalization. Typically, hospitalization lasts about 2 to 3 weeks, and proper antiviral treatment is necessary. Additionally, there are other forms of encephalitis caused by different viruses that are relatively milder and may even have a certain degree of self-healing properties. Generally, resting well, drinking plenty of water, and consuming fresh vegetables and fruits can lead to recovery. Therefore, whether hospitalization is necessary for encephalitis depends on the severity of the condition and the assessment of which virus has caused the infection. It cannot be generalized.
How is encephalitis diagnosed?
The diagnosis of encephalitis relies on the following aspects. First, it is based on clinical manifestations. If the patient clearly exhibits symptoms such as headache, fever, nausea, vomiting, and signs of increased intracranial pressure, and physical examination shows positive signs of meningeal irritation, then there is a high suspicion of encephalitis. Second, various auxiliary tests can be conducted. Initially non-invasive tests such as electroencephalograms (EEG) and magnetic resonance imaging (MRI) of the skull can be completed. If the MRI reveals significant abnormalities, such as abnormal signals in the frontal and temporal lobes including the hippocampus, then viral encephalitis should be highly suspected. If the EEG shows moderate abnormalities or increased slow waves, it also indicates damage to the cerebral cortex, serving as an indirect indicator of encephalitis. Third, a lumbar puncture can be performed to ascertain any abnormalities in the cerebrospinal fluid (CSF) routine and biochemical tests. If the cell count is elevated beyond ten times the normal value, an inflammatory infection is considered. There is often a minor to moderate increase in protein. The levels of glucose and chloride may decrease in bacterial and tuberculous encephalitis, while they are generally normal in viral encephalitis.