Colon cancer

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Written by Liu Liang
Oncology
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The difference between rectal cancer and colon cancer lies in the location of the cancer. Rectal cancer occurs in the rectum, which is the final part of the large intestine, while colon cancer occurs in other parts of the colon.

Rectal cancer and colon cancer are collectively referred to as colorectal cancer, named according to the different locations where the tumors occur. Rectal cancer occurs in the rectum. Colon cancer includes tumors in the transverse colon, descending colon, ascending colon, and sigmoid colon, and tumors in these areas are called colon cancer. Both are known as colorectal cancer, and they exhibit similar clinical manifestations, including rectal bleeding, abdominal pain, and changes in bowel habits, such as constipation, diarrhea, alternating constipation and diarrhea, and changes in stool shape, such as narrowing of the stool. They are merely named differently based on the location of the tumors and are collectively referred to as colorectal cancer.

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Written by Sun Wei
Surgical Oncology
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Is minimally invasive surgery suitable for transverse colon cancer?

Transverse colon cancer can also be considered for minimally invasive surgical treatment. The main procedure involves a complete resection of the transverse colon, and sometimes, it may require the resection of part of other organs. For instance, if the cancer has invaded the splenic region of the colon, a splenectomy may be necessary. If there is invasion into the liver area, partial liver resection may be needed. In cases where minimally invasive surgery is not suitable or inconvenient, it is also possible to switch to open surgery. The goal is to completely remove the tumor. Whether minimally invasive or traditional surgery is used, it is just a method of operation. Additionally, postoperative adjunct chemotherapy and other comprehensive treatments are necessary.

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Written by Sun Wei
Surgical Oncology
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What are the symptoms of transverse colon cancer?

Transverse colon cancer is a type of colon cancer, belonging to malignant tumors of the digestive system. The main symptoms may include rectal bleeding, narrower stools, increased frequency of defecation, diarrhea, and it may also cause constipation. For instance, if the tumor in the transverse colon is large enough to block the intestinal lumen, it could lead to difficulty in defecating. Constipation or even signs of intestinal obstruction could occur. Generally, a diagnosis can be confirmed through an endoscopic biopsy. After diagnosis, transverse colon cancer can be treated surgically, primarily through curative surgery, followed by adjuvant chemotherapy and other comprehensive treatments.

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Written by Shen Jiang Chao
Radiology
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Colorectal Cancer CT Manifestations and Differential Diagnosis

Early-stage colon cancer is difficult to clearly detect on a CT scan. In the moderate to late stages, colon cancer has more typical manifestations on CT, mainly characterized by thickening of the colon wall, irregular narrowing of the intestinal lumen, and stiffness of the intestinal wall. After enhancement, significant enhancement can be observed. The pericolonic fat space may appear blurred, and in the late stages, small lymph nodes can be seen, and even distant metastasis, most commonly to the liver, can be detected. It is necessary to differentiate colon cancer from colonic inflammation. Inflammatory lesions are usually more widespread and have typical clinical features such as fever and abdominal pain. It is also necessary to differentiate from lymphoma, as lymphomas also cause narrowing of the intestinal lumen but the narrowing is not eccentric and the intestinal wall remains soft, generally not leading to obstruction, whereas in late-stage colon cancer, colonic obstruction can be observed.

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Written by Wu Hai Wu
Gastroenterology
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Is dry, pellet-like stool a symptom of colon cancer?

Dry, granular stools are not necessarily symptoms of colon cancer, but patients with colon cancer may also experience dry, granular stools. Therefore, after exhibiting the above symptoms, patients need to promptly complete an electronic colonoscopy to confirm the diagnosis of the disease. For example, if the symptoms are due to colon cancer, aggressive surgical treatment should be taken, followed by comprehensive treatment including radiotherapy and chemotherapy. If the symptoms are due to functional indigestion causing constipation, treatment should involve using medications to regulate the intestinal flora and relieve constipation.

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Written by Sun Wei
Surgical Oncology
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Late stage survival of transverse colon cancer

Late-stage colon cancer can still potentially allow for a relatively long survival time, such as living more than one year, two years, or even three to five years. Of course, this also depends on the treatment provided. Generally, it may not be possible to perform curative surgery directly in the advanced stages, but preoperative neoadjuvant chemotherapy, targeted therapy, and so on, can be administered first. If these treatments can reduce the size of the tumor and lower its stage, there could still be a chance for surgical treatment later. Clinically, if there is no recurrence after more than five years, it is considered to have achieved a clinically curative effect. For instance, surpassing five years can possibly mean extending survival beyond ten years or even longer. However, treatment for late-stage patients needs to be adjusted as it proceeds, and it is impossible to specifically determine how long one can live.

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Written by Sun Wei
Surgical Oncology
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Can advanced colorectal cancer be cured?

Complete cure is often difficult to achieve in the middle and late stages of colorectal cancer. Of course, it is possible to control the progression of the lesion and then prolong survival. For middle and late-stage colorectal cancer, if the treatment is reasonable or effective, it is possible to survive for more than three years, five years, or even longer. Clinically, surviving more than five years without recurrence is considered a clinical cure. Of course, there is still a possibility of recurrence after five years, but the probability of recurrence will be much lower. If one can survive more than ten years, or even 20 years without recurrence, it is basically considered a cure, but regular check-ups are still necessary afterward, as it cannot be guaranteed that there will be no recurrence. For the middle and late stages of colorectal cancer, surgical treatment should be pursued whenever possible, followed by a combination of chemotherapy, radiotherapy, and targeted therapy after surgery.

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Written by Wu Hai Wu
Gastroenterology
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What are the symptoms of stool in colon cancer?

The stool of colon cancer generally appears as mucoid or purulent bloody stool, or there is alternation of diarrhea and constipation. The diagnosis of colon cancer mainly relies on electronic colonoscopy, and routine blood tests as well as carcinoembryonic antigen tests are also of certain reference value. Patients with colon cancer often present with symptoms like anemia and weight loss. Therefore, it is crucial for patients with colon cancer to obtain a definitive diagnosis as early as possible. In addition, early surgical treatment should be adopted. After surgery, adjunct treatments such as radiotherapy and chemotherapy should also be administered.

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Written by Sun Wei
Surgical Oncology
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How long can one live after colon cancer surgery?

If colon cancer can be treated surgically, generally, the outcomes might be quite good. It often applies to cancer in relatively early stages, with potentials to survive for over three years, five years, or even longer. Of course, there are cases of colon cancer that are discovered in later stages, where complete surgical removal is not possible, and only palliative stoma surgery can be performed. In such situations, the survival time might be within three to five years, but the exact life expectancy cannot be fully determined. Each individual's condition is different, and treatment must be adapted accordingly. Typically after surgery, treatments like chemotherapy, radiation therapy, and targeted therapy might be used in combination to prolong survival.

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Written by Gong Chun
Oncology
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Early symptoms of colon cancer

Colon cancer often does not have obvious symptoms in its early stages, and of course, the specific situation needs to be analyzed on a case-by-case basis, as it varies from person to person. As the disease progresses, some clinical symptoms may appear. The first one is changes in bowel habits and stool characteristics; there might be blood in the stool, changes such as an increased frequency of defecation, urgency followed by a feeling of incomplete evacuation, and a sensation of rectal fullness, along with possible changes in the shape or thinning of the stool. The second possible symptom is abdominal pain, which may also be accompanied by a feeling of bloating or abdominal discomfort. The third possibility is the symptoms of intestinal obstruction, which include cessation of bowel movements and passing gas. The fourth is that a mass may be felt in the abdomen. The fifth point is that some individuals, especially those in poor health, may experience symptoms of nutritional depletion from the tumor, such as anemia, weight loss, and fatigue. If there is early metastasis, symptoms corresponding to the metastasis may also appear.