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21
Zhang Lin
Rheumatology and Immunology Nephrology
About me
Dr. [Name], Associate Chief Physician at The Fourth Hospital of Changsha City.
Graduated from the Xiangya Medical College of Central South University, with over twenty years of experience in nephrology and rheumatology immunology. Has been involved in clinical, teaching, and research work, co-authored 1 monograph, participated in multiple national and provincial projects, and published over ten academic papers, two of which were included in SCIE.
Currently serves as the Director of the MDT Research Laboratory at the Changsha City Digestive Surgery Institute, Associate Chief of Nephrology and Rheumatology Department at The Fourth Hospital of Changsha City, member of the Quality Control Committee, Medical Accident Appraisal Committee, and Academic Committee of The Fourth Hospital of Changsha City, as well as a member of the Changsha Municipal Committee of the Chinese People's Political Consultative Conference.
Proficient in diseases
Diagnosis and treatment of acute and chronic kidney disease, as well as secondary kidney disease, and rescue of critical conditions
Voices
What should I do if lupus causes hair loss?
What should be done when a lupus patient experiences hair loss? Patients with lupus should keep their hair clean in daily life, not use too much shampoo when washing their hair, avoid dyeing or perming their hair, and reduce the damage to hair from chemical products. This prevents rashes or worsening rashes caused by allergies to hair dyes and damage to hair quality from perming. If hair loss occurs due to the effect of medications, patients can choose to wear a wig during treatment. After chemotherapy ends, new hair will grow, so patients need not worry excessively. Maintaining a pleasant mood is also quite important for recovery from the disease. The basic pathological change in lupus patients is vasculitis. When the small blood vessels in the skin become inflamed, the nutrient supply to the hair follicles is disrupted, which can easily lead to hair loss and affect hair growth. Generally, hair can regrow after the disease is controlled. If hair loss occurs again, it could be a symptom of a disease relapse.
What are the symptoms of the early stage of lupus erythematosus?
The main symptom in the early stage of lupus is the appearance of a butterfly-shaped rash on the face, with most patients initially exhibiting these rashes, some of which are not butterfly-shaped. The rash can also appear on fingers, palms, and around the nails. Additionally, over 80% of patients experience unexplained fevers, which are irregular and can sometimes reach up to 40 degrees Celsius. Some patients also experience joint pain in the early stages of the disease, mainly starting with pain in larger joints such as the elbows, knees, and ankles. If joint pain is accompanied by fever, rash, and a decrease in white blood cells, it is advisable to promptly visit a hospital for an examination to check for lupus. Some patients may also experience Raynaud's phenomenon and photosensitivity in the early stages of lupus. There are no fixed symptoms in the early stages of lupus; it is mainly important to observe oneself regularly and seek medical attention if feeling unwell.
Can lupus be treated without steroids?
Hormones are currently the first choice of drugs for treating lupus erythematosus, and there are no other drugs that can replace them temporarily, so we still recommend using hormones for treatment. Hormones can quickly and effectively suppress the immune response, reducing the damage to the patient's body from the inflammatory substances released during the immune response. This kind of immune-suppressive and anti-inflammatory action is a protective therapeutic effect on the body. Although long-term use of large doses of hormones has certain side effects, it can quickly block the development of the disease and alleviate the condition. The function of hormones cannot be replaced by any other drug at present, so, no matter what stage the lupus erythematosus patients are in and regardless of the type of damage, hormones are the first choice of drugs. Hormones have many side effects, therefore, we need to use hormone drugs for treatment rationally and standardized under the guidance of a doctor, and should not take them arbitrarily to avoid serious consequences.
Lupus is what disease?
Lupus erythematosus, also known as systemic lupus erythematosus, is a chronic autoimmune disease involving multiple systems and organs. Patients' serum contains various autoantibodies, with the main pathological changes being inflammatory reactions and vascular abnormalities. Most patients exhibit butterfly-shaped erythema on the bridge of the nose and cheeks, which is the most characteristic manifestation of lupus erythematosus. The clinical presentations of systemic lupus erythematosus are diverse, generally characterized by the "four multiples": involvement of multiple systems, multiple organs, multiple autoantibodies, and a higher prevalence among women of childbearing age. Without proper and effective treatment, the mortality rate is high, with the main causes of death being infections, renal failure, and damage to the central nervous system.
How is lupus treated?
The treatment of lupus erythematosus mainly involves the following aspects: Firstly, mild patients can be treated with antimalarial drugs, such as chloroquine or hydroxychloroquine, thalidomide, and low-dose corticosteroids; moderate active patients can receive individualized treatment with corticosteroids, and immunosuppressants may be used when necessary; for severe patients, corticosteroids are the preferred treatment, combined with immunosuppressants such as cyclophosphamide. Secondly, for lupus crisis patients, treatment can involve immunoglobulin, high-dose corticosteroid pulse therapy. Thirdly, biologics, such as anti-CD20 monoclonal antibodies, plasmapheresis, and autologous stem cell transplantation, are also used clinically. Medication for treating lupus erythematosus should be used under the guidance of a doctor, and self-medication should be avoided to prevent serious consequences.
For lupus, register under the department of Rheumatology.
Patients with lupus should visit the Department of Rheumatology and Immunology, as lupus is a clinically complex autoimmune disease. Many people think that lupus is a skin disease, but this is not the case. Lupus is a rheumatic and immunological disease, belonging to the category of rheumatic immunological diseases, and is an uncommon autoimmune disease.
Will the rash of lupus fade away?
Patients with lupus often experience recurrent, stubborn skin lesions on their hands or face, and some may even develop ulceration, atrophy, or scarring on top of the existing erythema. Most lupus patients exhibit erythema, centered around the bridge of the nose and appearing on the cheeks. The lesions are disc-like on both sides with generally clear boundaries, either flat or slightly raised, and are categorized as exudative inflammation. Depending on the severity of the inflammation, the erythema can range from light red, bright red to purple-red. In severe cases, localized edema resembling erysipelas may occur, and scaling and hyperpigmentation may appear as the inflammation subsides. Facial rashes generally resolve, and most rashes do not leave marks after resolution. If hyperpigmentation remains after the erythema has resolved, it suggests a good prognosis. However, erythema in other areas, such as acral erythema and reticular cyanosis, may last for varying durations depending on the patient's individual condition.
Can lupus be cured?
Lupus erythematosus currently has no cure in clinical practice. However, an early diagnosis and treatment can significantly prolong the life expectancy of patients. Compared to the past, with standardized and effective individualized treatments, the 5-year survival rate can reach 95%, and the 10-year survival rate can reach 84%. However, the cause of lupus erythematosus is unclear, and no method can completely cure the disease. It is important to emphasize that there are already some medications available clinically that can alleviate the symptoms, allowing patients to live normal lives and work normally. Additionally, it is crucial not to resort to desperate measures by seeking random treatments or believing in folk remedies and secret family recipes shared by others. Such actions can not only delay proper treatment and waste money but also worsen the condition due to unclear formulations.
What should I do if lupus causes a cold and cough?
When patients with lupus erythematosus experience a cold and cough, we should first conduct a routine blood test to see if it is caused by an infection, and then treat the symptoms accordingly. If the patient has a cough with phlegm, we should first help the patient clear the phlegm to avoid choking. Patients with lupus erythematosus should not take medication at will. If medication is needed to treat the cold and cough, it should be used under the guidance of a doctor.
What causes lupus erythematosus?
The cause of lupus erythematosus is not yet very clear. It is generally believed that the disease is caused by a combination of factors including genetics, environment, estrogen levels, and drugs, leading to immune disorder and consequently the onset of this disease. Studies have found that factors directly related to the onset of lupus erythematosus include ultraviolet rays causing apoptosis of epidermal cells, exposure of new antigens becoming autoantigens, and infections; Other possible related factors include drugs such as hydralazine and isoniazid, as well as food dyes, hair dyes, celery, figs, mushrooms, smoked foods, psychological stress, etc.; it may also be related to factors such as tobacco, vinyl chloride, asbestos, and vaccinations.