Erysipelas is an infectious disease that commonly affects the lower legs and face. Once erysipelas is diagnosed, penicillin is the recommended treatment. However, if there is an allergy to penicillin, cephalosporins or quinolones can be used as alternatives. Generally, intravenous infusion is necessary; oral administration alone is not effective. Intravenous medication is required to achieve the best anti-inflammatory treatment results.