Currently, most of the drugs used to treat vitiligo are traditional Chinese medicines, and they generally have relatively low side effects. However, because the effects of treatment for this disease are slow and the treatment cycle is long, long-term treatment is needed. Therefore, the biggest side effect of long-term oral administration of traditional Chinese medicines is the potential damage to the liver. During the entire treatment process, liver function can be rechecked after using the medication for three months. If the liver function is normal, these medicines can continue to be used. During the medication process, some liver-protecting drugs can also be taken orally. Commonly used topical medications can initially irritate the skin, causing symptoms such as redness, itching, or blistering, but these symptoms will gradually disappear with long-term use.