Patients with depression primarily exhibit symptoms of low mood. They often experience persistent sadness and pessimism. Patients might find it difficult to feel happy, appear gloomy, and are unable to experience joy, particularly in activities that they used to find interesting. In severe cases, they might feel hopeless, in despair, and have thoughts of death, leading to an overwhelming sense that each day is unbearably long. Furthermore, patients might feel that life isn't worth living and that their existence has no meaning, which can lead to thoughts or actions of suicide or self-harm. In this emotional state, their self-evaluation is also typically low; they might feel utterly worthless, viewing themselves as a burden on their family and a parasite in society. Thus, feelings of worthlessness, helplessness, despair, and self-blame are significantly more pronounced.