How is rheumatoid arthritis treated?

Written by Yang Ya Meng
Rheumatology
Updated on March 07, 2025
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The treatment of rheumatoid arthritis mainly falls into three categories:

The first category includes anti-inflammatory and pain-relief medications, which are further divided into non-steroidal pain-relief drugs and low-dose corticosteroids.

For rheumatoid arthritis, the most crucial treatment involves the choice of the second category: slow-acting drugs. Common drugs used in treating the key aspects of rheumatoid arthritis include immunosuppressants such as methotrexate and leflunomide.

If the patient does not respond well to the above two conventional treatments, a third option that can be considered is treatment with biological agents. Commonly used biological agents include tumor necrosis factor antagonists. Before using biological agents, it is necessary to strictly rule out hepatitis, tuberculosis, and neoplastic diseases.

(Please use medication under the guidance of a doctor)

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Written by Yang Ya Meng
Rheumatology
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Is rheumatoid arthritis serious?

Patients with rheumatoid arthritis, if treated reasonably and formally, can achieve clinical remission, so in this sense, rheumatoid arthritis is not severe. However, if patients do not adhere to formal treatment for a long time, after a long period, they may develop joint deformities and ankylosis, resulting in disability. From this perspective, rheumatoid arthritis should be taken seriously. Commonly used drugs for treating rheumatoid arthritis include anti-inflammatory pain relievers, with non-steroidal pain relievers being the most commonly used, such as sustained-release diclofenac sodium tablets. The most important step in treating rheumatoid arthritis is the selection of immunosuppressants, with common immunosuppressants including methotrexate and leflunomide. (Medication should be used under the guidance of a doctor based on specific circumstances.)

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Written by Yang Ya Meng
Rheumatology
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Rheumatoid Arthritis Diagnostic Criteria

The diagnostic criteria for rheumatoid arthritis include the following aspects: The first is symmetrical joint pain, primarily characterized by tenderness and swelling in the metacarpophalangeal joints, proximal interphalangeal joints, and both wrists. Secondly, it also includes abnormalities in inflammation markers, which comprise erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP), along with abnormalities in certain antibodies, mainly rheumatoid factor, CCP antibodies, and AKA antibodies. If the above symptoms are present, and these inflammation markers and antibodies are found to be abnormal upon blood testing, a diagnosis of rheumatoid arthritis can be made.

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Written by Liu Li Ning
Rheumatology
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How is rheumatoid arthritis treated?

The treatment of rheumatoid arthritis is divided into general treatment and pharmacological treatment. General treatment mainly involves avoiding overexertion, having a light diet, and not staying up late. Pharmacological treatment is mainly divided into treatment during the acute flare-up phase and the remission phase. The acute phase focuses on anti-inflammatory and pain relief treatments, with non-steroidal anti-inflammatory drugs (NSAIDs) as the first choice, such as etoricoxib, meloxicam, or celecoxib. If the effect is not satisfactory, low-dose corticosteroid therapy may be combined. In the remission phase, slow-acting anti-rheumatic drugs are preferred, such as methotrexate, leflunomide, or sulfasalazine. If the slow-acting anti-rheumatic drugs are not effective, biologic agents such as tumor necrosis factor antagonists or JAK inhibitors may be combined.

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Written by Li Jing
Rheumatology
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Does rheumatoid arthritis hurt?

Firstly, rheumatoid arthritis belongs to autoimmune diseases and is a chronic condition. The main symptoms include symmetric pain in multiple joints across the body, accompanied by morning stiffness, which is why joint pain occurs and is the most common symptom. The onset is slow for most people, but some experience an acute onset, with joint mobility issues appearing within a few weeks or days. Therefore, this disease cannot be cured; it can only be managed with medications to control symptoms, delay the deformity of joints, reduce disability rates, and enhance the quality of life, which are the objectives of comprehensive treatment. It is important to avoid exposure to cold and fatigue in daily life, avoid contact with cold water, keep warm, also avoid raw and cold foods, spicy and irritating foods, and eat more light, easy-to-digest, and high-protein foods to boost the immune system.

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Written by Li Jie
Orthopedics
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How to treat rheumatoid arthritis?

Rheumatoid arthritis-induced joint pain has several distinct characteristics: The first is that it initially affects the small joints of the limbs, typically involving the hands, feet, wrists, and ankles, before spreading to larger joints. It rarely starts in the large joints first. Secondly, the onset is generally symmetrical, meaning it seldom affects just a single limb or joint. Typically, if the disease manifests, it affects both limbs simultaneously. Another characteristic is significant morning stiffness, meaning a feeling of stiffness upon waking up in the morning. Generally, by combining auxiliary tests such as blood tests and imaging, a clear diagnosis of rheumatoid arthritis can be made. Once diagnosed, it is advised that patients seek treatment at a reputable hospital in the rheumatology and immunology department or orthopedics, targeting specific treatments and avoiding unlicensed practitioners. Common rheumatoid arthritis treatment plans start with medications to alleviate symptoms, using immunosuppressants. In severe cases, a small, short-term dose of steroids may be used. Additionally, symptomatic treatment may include topical applications of ointments to improve blood circulation, reduce swelling, and alleviate pain. Patients can also take non-steroidal anti-inflammatory drugs orally to relieve symptoms. Furthermore, traditional Chinese medicine is also a very effective method, and patients can take specific herbal medicines as symptomatic treatment for rheumatic joint pain, which are also very effective. (Please follow a professional physician's guidance when using medications and do not medicate blindly.)