When patients experience crusting of angular cheilitis, it is not advisable to apply fresh aloe directly because removing some scabs can lead to local infections. The components in commonly cultivated aloe are not suitable for applying on wounds as they cannot guarantee sterile procedures and may cause allergic reactions during use. Some aloe plants may be exposed to pesticides during growth, which could hinder the healing process of patients' wounds. Therefore, it is recommended that patients use aloe vera gel instead of applying fresh aloe directly, as aloe vera gel is processed through manual operations and is suitable for use on human skin.