Urticaria, commonly known as hives, occurs when there is a localized swelling due to temporary increased vascular permeability of the skin and mucous membranes. It can be divided into acute urticaria and chronic urticaria. Acute urticaria often has a sudden onset. Chronic urticaria is characterized by recurrent skin lesions for more than six weeks, with episodes occurring at least twice a week, termed as chronic urticaria. The preferred treatment for acute urticaria is the use of second-generation H1 receptor antagonists with a strong sedative effect. The combination of vitamin C and calcium supplements can reduce vascular permeability and have a synergistic effect with antihistamines. For chronic urticaria, the treatment of choice is also second-generation H1 receptor antagonists. When one medication is ineffective, two to three drugs may be combined or alternated. It is also recommended to combine Chinese medicine to adjust the overall physical condition while gradually reducing the dosage of Western medicine to control the condition.