Is glioma cancer?

Written by Gao Yi Shen
Neurosurgery
Updated on September 04, 2024
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Gliomas are the most common type of malignant tumor within the skull, and they are also a form of cancer. Cancer is a very broad term essentially describing a process where some cells proliferate abnormally and differentiate without dying, and gliomas proliferate in the same way. To give an analogy, think of a bunch of villains: if there are heroes to suppress and resolve these villains, then generally, people would not develop tumors. However, if this group of villains gradually becomes stronger and defeats the heroes, then these villains gather within the body, forming a tumor. The same principle applies to the formation of cancer. Therefore, for such cases, it is crucial to detect cancer early and begin the appropriate treatment. Early treatment can have some very beneficial effects on the prognosis for the patient.

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Written by Gao Yi Shen
Neurosurgery
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Glioma Symptoms

The symptoms of glioma are numerous, and it is essential to make judgments based on the situation. The most common clinical manifestations are headaches, dizziness, nausea, and vomiting. These symptoms may persist for a relatively long period and are relatively mild, not immediately noticeable at the time. Additionally, some patients may experience a decline in cognitive function, colloquially described as becoming less intelligent. This is especially common in gliomas of the frontal lobe. If the glioma is located in the occipital lobe, it often causes visual disturbances, such as blurred vision and visual field defects. In cases of temporal lobe gliomas, frequent seizures and impaired limb mobility may occur. For cerebellar gliomas, symptoms can include a decline in cognitive function and ataxia, among others.

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Written by Chen Yu Fei
Neurosurgery
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Glioma Symptoms

For patients with glioma, they often exhibit certain degrees of headache and dizziness, with headaches typically located bilaterally in the frontal or temporal regions. The nature of the pain is relatively sharp, manifesting as intermittent attacks that progressively worsen over time. Long-standing gliomas easily induce a notable increase in intracranial pressure, presenting with severe headaches, nausea, vomiting, and even a decrease in vision or visual field defects. When the glioma is located in the parietal lobe and affects important motor function areas, it can lead to unilateral or bilateral limb weakness, numbness, pain, and possibly even trigger hemiplegia.

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Clinical manifestations of glioma

For patients with glioma, as it is a malignant tumor with a rapid growth rate, they may exhibit severe symptoms at the early stage of the disease, including severe headaches, dizziness, nausea, vomiting, loss of appetite, poor mental state, poor sleep quality at night, frequent insomnia and nightmares, and easy waking up. As the tumor increases in size, it often causes an increase in intracranial pressure. In severe cases, this may lead to optic disc edema, decreased vision, and visual field defects. Additionally, some patients may experience impairment in motor functions, manifesting as hemiplegia, and in some cases, aphasia. It is advised to undergo surgery in the early stages, followed by radiotherapy and chemotherapy.

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Written by Gao Yi Shen
Neurosurgery
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Is a glioma benign or malignant?

Glioblastoma is the most common form of malignant tumor inside the skull, and the vast majority of glioblastomas are highly malignant. Once changes in this condition are detected, generally, the patient doesn't have much time left. If it is a relatively better glioblastoma, which means it is highly differentiated, the survival time is about 1-2 years. For some poorer glioblastomas, or those with low differentiation, their survival period is often only about six months, and they continuously spread along with nerve fibers to the surrounding areas. They might even metastasize to distant places through cerebrospinal fluid, blood, lymph, and other means. Therefore, even if surgery is used to remove a single lesion, other parts of the body may still demonstrate metastatic lesions. Hence, the treatment approach for this is comprehensive.

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Written by Chen Yu Fei
Neurosurgery
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Early symptoms of glioma

For patients with glioma, in the early stages of the disease, symptoms often manifest as mild headaches, dizziness, nausea, and vomiting. The symptoms are usually mild and tolerable for patients, and most patients do not pay enough attention, which can easily lead to missed and misdiagnosis. However, as the tumor volume increases, the patient's symptoms of headache, dizziness, and other discomforts gradually worsen, and may even show episodic outbreaks and a persistent worsening state. In addition to headaches and dizziness, some patients also exhibit significant motor dysfunction, exhibiting symptoms such as hemiplegia and aphasia. Patients with severe conditions may even experience widespread intracranial pressure increase, and life-threatening conditions due to the induction of brain herniation.