Symptoms of neuroblastoma recurrence

Written by Chen Yu Fei
Neurosurgery
Updated on November 08, 2024
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For neuroblastoma, when the tumor recurs, the patient's original symptoms such as headaches, dizziness, nausea, and vomiting will reappear, occurring intermittently and worsening persistently. Most patients will experience significant increased intracranial pressure, and even frequent nausea and vomiting. Additionally, some neuroblastoma patients experience severe vertigo, especially when changing body positions, where the vertigo is particularly pronounced. For such patients, when the above symptoms and signs occur, they should go to a local hospital as soon as possible for a reassessment using cranial MRI to monitor changes in their condition.

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Written by Chen Yu Fei
Neurosurgery
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Causes of Neuroblastoma

Currently, there is no definitive conclusion about the specific causes of neuroblastoma, but most scholars believe that the occurrence of neuroblastoma is the result of congenital genetic factors combined with acquired factors. For patients with neuroblastoma, there is often a family history of genetic diseases showing a familial clustering tendency. In addition, poor living environments and habits, including exposure to radioactive contamination or prolonged exposure to electromagnetic radiation, may also contribute to the development of neuroblastoma.

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Written by Chen Yu Fei
Neurosurgery
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Late-stage symptoms of neuroblastoma

For patients with neuroblastoma, they often experience significant symptoms such as headaches, dizziness, nausea, and vomiting. The intracranial pressure continuously rises, leading to noticeable optic atrophy, vision loss, and visual field defects. When the tumor volume further increases, it may also compress the surrounding tissues, causing apparent cranial nerve dysfunction. Moreover, in the late stages of the disease, the tumor can spread to other parts of the body via the bloodstream, forming metastases. Additionally, it is likely to disseminate through the cerebrospinal fluid.

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Written by Chen Yu Fei
Neurosurgery
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Neuroblastoma treatment

Neuroblastoma is relatively considered a malignant tumor, and its growth rate is quite rapid. It often adheres to surrounding tissues in the early stages, which makes it very difficult to completely remove surgically. However, even so, it is still advisable to opt for surgical treatment once neuroblastoma is detected. The tumor should be completely removed surgically, and a small amount of tumor tissue should be retained for pathological examination after removal. Based on the results of the pathological examination, it will be determined whether additional treatments such as radiotherapy or chemotherapy are needed. Furthermore, since some neuroblastomas are sensitive to radiotherapy, it is recommended to promptly take the patient to a local hospital for treatment after surgery.

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Written by Chen Yu Fei
Neurosurgery
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How do you get neuroblastoma?

Currently, there is no consensus on the specific causes of neuroblastoma. In most cases, it is believed to be caused by the failure of primitive myeloid epithelial cells to continue differentiating, which is somewhat linked to congenital genetic factors. Additionally, poor lifestyle choices and exposure to certain chemical carcinogens, including long-term exposure to radiation, can potentially lead to neuroblastoma. Neuroblastoma is a highly malignant tumor that generally grows and develops rapidly. It often adheres to surrounding tissues in the early stages of the disease, making complete surgical removal quite difficult, and typically has a poor prognosis.

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Written by Chen Yu Fei
Neurosurgery
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Neuroblastoma is what disease

Neuroblastoma is a highly malignant epithelial neurocyte tissue tumor, which is relatively aggressive. Often in the early stages of the disease, the tumor tissue adheres to surrounding brain tissue, nerves, and blood vessels, making it impossible to completely remove it surgically. The residual tumor cells quickly recur over time. As a result, most neuroblastoma patients have a poor prognosis and short survival time, even with effective surgical treatment, including postoperative radiotherapy and chemotherapy. Therefore, it is recommended that those diagnosed with neuroblastoma undergo early further examinations and treatments.