In cases of pneumoconiosis reaching stage three, radiological examinations generally reveal a large area of fibrotic changes in the lungs. Clinical symptoms in such patients tend to be relatively severe, typically including notable cough, phlegm, shortness of breath, and respiratory difficulty. Some may even experience fevers, headaches, dizziness, and general weakness due to concurrent bacterial infections.

For the treatment of stage three pneumoconiosis, there are generally no specific effective medications available clinically. Treatment primarily focuses on symptomatic relief and reducing the occurrence of complications. Patients often use medications such as cough suppressants, expectorants, and asthma relief to manage symptoms. Additionally, it's advisable to use anti-fibrotic drugs to slow the progression of pulmonary fibrosis.