How is obesity treated?

Written by Luo Juan
Endocrinology
Updated on September 13, 2024
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Regarding the treatment of obesity, the cause of obesity must first be identified. For patients with simple obesity, the primary approach involves lifestyle interventions, including exercise and diet.

The diet should involve a calculation of caloric intake based on activity levels, generally focusing on a low-calorie or very low-calorie intake. Additionally, it is recommended to engage in suitable aerobic exercises.

Currently, there are products available such as fat enzyme inhibitors that reduce weight by inhibiting the absorption of fats in the intestines. Also, in the United States, GLP-1 agonists are available for the treatment of simple obesity. If obesity is caused by certain medical conditions, such as an endocrine disorder known as Cushing's syndrome, which can also lead to obesity, treatment should first address the primary disease, which would also resolve the obesity.

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Written by Luo Juan
Endocrinology
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symptoms of obesity

Regarding the symptoms of obesity, they vary with the type of disease. For example, in secondary cases, there are clinical manifestations of the primary disease. For instance, obesity caused by hypothyroidism may also present with fatigue, poor appetite, dry skin, etc. Some people have obesity due to insulinoma or recurrent hypoglycemia, leading to repeated eating. The clinical manifestations also include symptoms of hypoglycemia such as palpitations, trembling hands, sweating, and a sense of hunger. If it is a case of simple obesity, generally, men primarily show an apple-shaped obesity, with fat accumulated mainly above the waist. In contrast, women exhibit a pear-shaped obesity, with fat accumulation below the waist, such as in the lower abdomen, buttocks, and thighs. Of course, related to obesity, there are also manifestations of cardiovascular diseases, high blood pressure, diabetes, etc. Some people with obesity may also experience sleep apnea syndrome, venous thrombosis, and so on. Studies suggest that the incidence of malignant tumors is also higher in patients with obesity. Because patients with long-term obesity carry excess weight for a long period, they may experience lower back pain, joint pain, swelling, and are more prone to abrasion or combined fungal or purulent infections in the folds of the skin. Therefore, the clinical manifestations of obesity vary according to the cause of the disease.

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Written by Zhao Xin Lan
Endocrinology
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Is it difficult for people with obesity to get pregnant?

Patients with obesity, especially women with excessive abdominal fat, often experience disrupted hormonal balance due to altered levels of circulating sex hormones. This frequently leads to ovulatory abnormalities and excess androgens, often accompanied by reproductive dysfunction. As a result, such conditions manifest as difficulty in conceiving, and are commonly associated with menstrual irregularities, amenorrhea, and infertility. Some patients may also develop polycystic ovary syndrome. Even in pregnant obese women, the risks of diabetes and hypertension increase, as do the risks of complications during childbirth and congenital abnormalities in their infants. Therefore, it is crucial for women of childbearing age to maintain a normal weight.

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Written by Tang Zhuo
Endocrinology
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Obesity weight loss methods

The treatment of obesity involves two main components. One is reducing calorie intake and the other is increasing calorie consumption, mainly emphasizing a comprehensive treatment based primarily on diet and exercise. Secondly, medications or surgical treatments can be utilized. In the case of secondary obesity, it is important to treat the underlying cause. So, what is behavioral therapy? It involves educating patients and their families about obesity and its risks, enabling them to cooperate with the treatment, adopt a healthy lifestyle, change dietary and exercise habits, and maintain these changes consciently in the long term as the foremost and most important measures in the treatment of obesity. Thirdly, controlling diet and increasing physical activity are crucial. Individuals with mild obesity can control their total food intake with a low-calorie, low-fat diet. For those with moderate to severe obesity, total calorie intake should be strictly controlled, with women limited to 1200-1500 kcal per day and men to 1500-1800 kcal per day. Following this standard, a weight loss of 1-2 pounds per week can be achieved. Furthermore, for severe obesity, medications can be used to reduce weight, which can then be maintained. If necessary, surgical procedures such as jejunoileal bypass or biliopancreatic diversion surgery can be considered.

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Written by Li Lang Bo
Endocrinology
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Causes of Obesity

In the medical field, obesity is categorized into two types: primary (simple) obesity and secondary obesity. Primary obesity occurs without any other physical diseases and is solely due to irregular lifestyle, unscientific eating habits, and lack of exercise, leading to weight gain. This type can be managed with lifestyle adjustments and proper dietary guidance to reduce weight. Secondary obesity, which is less common, often involves endocrine disorders such as Cushing's syndrome. This condition can arise from issues with the pituitary or adrenal glands, or other parts of the body such as tumors, leading to excessive secretion of cortisol. This in turn causes redistribution of body fat, leading to characteristic signs like moon face, buffalo hump, and accumulation of subcutaneous fat which are manifestations of obesity. Additionally, conditions like hypothyroidism can lead to myxedema, contributing to obesity, as well as drug-induced obesity. Examples include patients with nephrotic syndrome or lupus who experience weight gain from prolonged use of corticosteroids. Therefore, the causes are diverse and require differential diagnosis by a specialist based on the individual's condition.

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Written by Tang Zhuo
Endocrinology
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Obesity can cause which diseases

Firstly, obesity, also known as adiposity, is a chronic metabolic disease caused by excessive accumulation or abnormal distribution of body fat. Diseases closely related to obesity include cardiovascular diseases, hypertension, diabetes, etc. Complications of obesity also include sleep apnea syndrome, venous thrombosis, and others. Moreover, the occurrence of malignant tumors increases with obesity, as prolonged obesity can lead to skin folds that are prone to abrasions and subsequent fungal or purulent infections.