Diabetic foot refers to those with a history of diabetes who subsequently develop skin ulceration and pus formation on the feet, which can progress to localized gangrene or gangrene of the entire foot. This condition is then termed as diabetic foot. It is usually due to three factors: The first is vascular factors, often accompanied by arterial narrowing in both lower limbs, leading to ischemia and hypoxia. The second is neurological factors, typically accompanied by peripheral neuropathy, causing numbness in both feet and insensitivity to pain, thus often pain is not felt. The third factor involves the presence of an infection. These three factors together make it easy for diabetic foot to develop. Therefore, most patients with diabetic foot do not feel pain. However, if the neuropathy is relatively mild or is a painful neuropathy, these patients may feel pain in their feet or at the site of skin ulceration.