Are pituitary tumors prone to recurrence?

Written by Chen Yu Fei
Neurosurgery
Updated on February 04, 2025
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Pituitary tumors in the brain are benign tumors that grow slowly. When the tumor size is relatively small, there are generally no clear symptoms or signs, and most patients can work, live, and study like normal people. It is recommended to treat pituitary tumors with surgical methods. Most pituitary tumors are benign. If they can be completely removed through microscopic surgery, or through the transnasal transsphenoidal approach, minimally invasive surgery can achieve ideal treatment results and generally will not recur. However, for individual patients with pituitary tumors, if the tumor is malignant, it may easily adhere to surrounding tissues in the early stages, making it difficult to completely remove surgically, thus it is prone to recurrence.

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Written by Chen Yu Fei
Neurosurgery
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What is a pituitary tumor?

Pituitary tumors refer to a type of benign tumor that occurs at the site of the pituitary fossa. Generally, they grow relatively slowly. In the early stages of the disease, there are usually no obvious symptoms or signs. Some patients may occasionally feel mild headaches or dizziness, which most can tolerate. As the size of the pituitary tumor gradually increases, it often affects the surrounding critical tissues, nerves, and organs, primarily impacting pituitary function, thereby leading to pituitary hypofunction. This affects the secretion of endocrine hormones in the body, causing abnormal secretion of endocrine hormones, and resulting in a series of symptoms and signs. For example, male patients may experience abnormalities in the secretion of male hormones, leading to difficulties with erection, while female patients are likely to experience menstrual disorders and irregular menstruation.

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Written by Chen Yu Fei
Neurosurgery
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Can pituitary tumors be cured?

Currently, for the treatment of pituitary tumors, it is generally recommended in clinical practice to opt for a complete resection via a transnasal-transsphenoidal approach. Most patients can achieve good therapeutic outcomes through surgery. The main goals of surgically treating pituitary tumors are to remove the tumor, decompress the visual pathways, and help restore and maintain the function of the pituitary and other neurological functions. Most patients can achieve good therapeutic results after treatment. Additionally, after receiving treatment, patients' original symptoms gradually alleviate or even disappear, and no longer worsen. Therefore, from this perspective, it is recommended that all symptomatic pituitary tumor patients should timely seek medical consultation at local hospitals and receive early treatment.

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Written by Chen Yu Fei
Neurosurgery
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Is a pituitary tumor easy to treat?

Our current understanding of pituitary tumors is quite deep, and we have accumulated rich treatment experience in the pathogenesis, disease progression, and treatment of pituitary tumors. Therefore, it is recommended to use surgical methods for pituitary tumor patients, especially those with obvious symptoms. Clinically, it is generally recommended to choose the transnasal-transsphenoidal approach for a complete resection of the pituitary tumor. For most patients, this can achieve good therapeutic effects. Moreover, with the continuous advancement of diagnostic techniques, early detection and treatment of small early pituitary microadenomas through complete surgical resection can also achieve good therapeutic outcomes.

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Written by Chen Yu Fei
Neurosurgery
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How many days of hospitalization for pituitary tumor surgery?

For patients with pituitary tumors, it normally takes about one to two weeks to undergo surgery and be hospitalized. After surgery, it is appropriate for patients to rest in bed and refrain from getting up too early, mainly to monitor for any occurrence of cerebrospinal fluid rhinorrhea. Premature activity might lead to cerebrospinal fluid rhinorrhea or even trigger intracranial infections. Additionally, after surgery, it is important to perform blood tests to check the levels of endocrine hormones in the body, primarily to assess whether important electrolyte and hormone levels are normal. If there are abnormalities, adjustments should be made promptly, and discharge can be considered once the patient's condition is stable.

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Written by Chen Yu Fei
Neurosurgery
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Postoperative complications of pituitary tumor surgery

For patients with pituitary tumors, a range of complications, sequelae, or concomitant ailments can easily occur after surgery. For instance, postoperative sellar hematoma may occur, and some patients may even experience the rupture of a pseudoaneurysm. Additionally, some patients may repeatedly suffer from headaches, dizziness, nausea, vomiting, and weakness in the limbs after surgery, along with significant memory decline, reduced cognitive function—including calculating ability, and orientation in time, space, and person—gradually diminishing. These are considered postoperative sequelae of pituitary tumor surgery.