The difference between pituitary tumors and pituitary adenomas

Written by Chen Yu Fei
Neurosurgery
Updated on February 23, 2025
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The difference between a pituitary tumor and a pituitary adenoma mainly lies in the extent of the affected tissue involved. Generally, pituitary tumors may have a broader range than pituitary adenomas, meaning that pituitary tumors include pituitary adenomas. Normally, a pituitary adenoma specifically refers to tumors occurring in the anterior lobe of the pituitary gland, as this lobe primarily consists of glandular tissue. Meanwhile, the posterior lobe of the pituitary is mainly neurohypophysis. Therefore, tumors typically referred to as pituitary adenomas occur in the anterior lobe. If a tumor is in the posterior lobe, it cannot be called a pituitary adenoma, but it still falls under the category of pituitary tumors.

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Written by Chen Yu Fei
Neurosurgery
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Is a 2cm pituitary tumor big?

In the case of pituitary tumors, if the size reaches two centimeters, it is relatively large. Under normal circumstances, pituitary tumors can be classified into several types based on their size: microadenomas are generally smaller than one centimeter, macroadenomas are larger than 1.0 centimeter, and giant adenomas are larger than 3.0 centimeters. Usually, a two-centimeter pituitary tumor is already considered a macroadenoma. Normally, such large pituitary tumors often compress the surrounding pituitary tissue, causing hypofunction of the pituitary tissue and significant hormonal disturbances, which can lead to a range of uncomfortable symptoms and signs in patients.

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Neurosurgery
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What should I do about a pituitary tumor?

When a pituitary tumor occurs, we generally recommend surgery as the treatment method. Of course, specific analysis should be done based on the individual circumstances of the patient before surgery. In cases where the tumor is small and there are no obvious clinical symptoms—discovered incidentally during other related examinations—such patients can temporarily take medication and should be closely monitored with regular follow-ups to observe any changes in their condition. However, for patients who have clear clinical symptoms and display endocrine hormone imbalances, such as men experiencing significant erectile dysfunction and women having menstrual disorders, surgery is generally recommended as the treatment method.

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Can pituitary tumors cause headaches?

For patients with pituitary tumors, headaches may occur. Most patients in the early stages often experience mild headaches located behind the eye sockets, the forehead, and on both sides of the temporal area. These headaches are generally tolerable and occur intermittently. They are mostly caused by the stimulation of the tumor or the increased pressure inside the sella. When the tumor enlarges to a certain extent and breaks upward through the diaphragm sellae, headaches are often alleviated. However, if the tumor further grows into surrounding tissues, it might compress important blood vessels and nerves, resulting in recurring pain with increasing severity.

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Neurosurgery
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How long does it take to recover after pituitary tumor surgery?

For patients with pituitary tumors, about six months to a year after undergoing surgery, as the endocrine hormones in the body gradually return to normal, the patient's original symptoms or signs gradually diminish or even disappear, and the quality of the body also gradually recovers. At this time, patients often recover well. For such patients, it is necessary to visit the local hospital regularly after surgery for follow-up appointments, to have a cranial MRI to help assess the effects of the pituitary tumor surgery recovery, and to have blood drawn to test the endocrine hormones in the body to see if they have returned to normal levels. If there are still abnormalities, it is advisable to take medication to regulate them.

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Written by Chen Yu Fei
Neurosurgery
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Is pituitary tumor surgery done under general anesthesia?

For patients with pituitary tumors, general anesthesia is typically recommended for surgery. Clinically, a combined inhalational and intravenous anesthesia approach is adopted for treatment. Before surgery, anesthesia induction is carried out to stabilize the patient, who then undergoes tracheal intubation for general combined anesthesia. As the surgery nears completion, appropriate medication may be used to help shorten the anesthesia process. After the surgery is fully completed, the patient is transferred to the recovery room. Once the anesthetic drugs are gradually metabolized and consciousness returns to clarity, the tracheal tube is effectively removed.