In the early stages, when the autoimmune destruction from Hashimoto's thyroiditis is not particularly severe and does not cause either hyperthyroidism or hypothyroidism, there may be no symptoms at all. As the immune response intensifies and leads to increased destruction of thyroid cells, transient thyrotoxicosis can occur, resulting in symptoms such as heat intolerance, trembling hands, and palpitations. The duration of these symptoms is related to the severity of the destruction. Generally, symptomatic relief can be achieved by administering beta-blockers. In the later stages, when the destruction of thyroid function in Hashimoto's is exacerbated, leading to hypothyroidism, symptoms such as cold intolerance, fatigue, and hair loss may occur. (Medication should be used under the guidance of a professional doctor.)