Is night blindness a recessive genetic disease?

Written by Tao Yuan
Ophthalmology
Updated on September 04, 2024
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Night blindness is not a recessive genetic disease; it is merely a symptom caused by many ophthalmic diseases. The primary manifestation is difficulty seeing in dim environments and requiring a longer time to adapt when moving from bright to dim settings. There are various causes of night blindness, with common ones including vitamin A deficiency, malnutrition of rod cells, and advanced glaucoma. Therefore, when a patient exhibits symptoms of night blindness, it is crucial to seek medical attention promptly. A doctor can determine the specific cause through a comprehensive examination and implement targeted treatment. The primary diseases causing night blindness are mostly non-hereditary; for example, vitamin A deficiency is mainly related to malnutrition and picky eating, which can be treated by supplementing vitamin A.

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Written by Li Zhuo
Ophthalmology
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Causes of Night Blindness

Night blindness generally falls into two categories. The first type is due to a deficiency in Vitamin A, which leads to abnormal metabolism of retinol, preventing the perception of low light and thus causing symptoms of night blindness. The other condition is retinitis pigmentosa, where the photoreceptor cells in our retina responsible for detecting light at night, mainly the rod cells, undergo premature apoptosis, resulting in poor light perception. Retinitis pigmentosa can be congenital, caused by genetic mutations or abnormalities, but it can also be secondary to other diseases. Conditions like choroiditis or choroid retinitis inflammation can lead to abnormalities in the rod cells, which can also result in night blindness. The specific causes need to be examined.

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Written by Li Zhuo
Ophthalmology
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Can people with night blindness undergo myopia surgery?

Night blindness is mostly due to abnormalities in the retinal pigment epithelial cells, because when these cells are abnormal, it leads to abnormalities in the rod cells, which sometimes leads to night blindness. This is because rod cells are responsible for seeing in low light, proving that this refractive system’s weakness is akin to a camera’s film being damaged. In the case of performing surgery for nearsightedness, it is primarily because there's an issue with the eye’s refractive system, similar to having a damaged camera lens. While a damaged lens can be repaired, if the film is faulty, even a perfectly repaired lens won't improve the camera's imaging function. Thus, night blindness primarily involves the retina, whereas surgery for nearsightedness mainly involves the lens and cornea. If the retina's condition is poor, then vision improvement from nearsightedness surgery will be limited because the effectiveness of such surgery relies on the pre-surgery vision achievable with glasses. If vision with glasses is inadequate, the surgical outcomes tend to be suboptimal. Generally, we do not recommend laser surgery for patients with night blindness.

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Written by Wang Hui Zhen
Ophthalmology
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What will happen if night blindness is not treated?

Night blindness, if left untreated, can progress slowly in some cases and more rapidly in others, potentially leading to blindness quickly. Therefore, it is recommended to visit a hospital for diagnosis and targeted treatment if night blindness occurs. Night blindness refers to the blurriness or even complete inability to see in low light conditions or at night, causing difficulty in movement. Night blindness can be categorized into congenital night blindness, acquired night blindness, and temporary night blindness. Congenital night blindness is mostly related to genetic factors. Patients are born with a deficiency in synthesizing rhodopsin, which leads to night blindness. It is recommended to supplement with Vitamin A as per medical advice, though the treatment effectiveness for congenital night blindness is generally poor, and gene therapy is considered a direction for the future. Acquired night blindness is often caused by diseases intrinsic to the eye, and it is advisable to actively treat the primary disease. Temporary night blindness is mostly due to a lack of Vitamin A in the diet or due to certain digestive system diseases that affect the absorption of Vitamin A; hence, it is recommended to supplement Vitamin A as advised by a doctor.

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Written by Tao Yuan
Ophthalmology
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Patients with night blindness are lacking something.

Night blindness is a common symptom in ophthalmology, referring to a condition where patients cannot see clearly in dim environments. Night blindness can be caused by various reasons, among which vitamin A deficiency night blindness occurs due to the patient's long-term picky eating or malnutrition, leading to insufficient intake of vitamin A. Vitamin A is an essential raw material for the synthesis of photosensitive substances in the retina, and its deficiency can lead to night blindness. Night blindness caused by retinal pigment degeneration, malnutrition of rod cells, and late-stage glaucoma does not involve a lack of nutritional elements in the patient's body. Instead, it results from damage to the rod cells in the retina or the nerve fiber layer, which prevents them from sensing light stimuli in dark environments.

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Written by Wang Hui Zhen
Ophthalmology
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Does night blindness also cause a decrease in vision during the day?

Patients with severe night blindness also experience a decline in vision during the day. Night blindness refers to the blurriness or complete inability to see in the dark or dimly lit environments, causing difficulties in movement. In severe cases, vision can also decline during the day. Night blindness can be categorized into congenital, acquired, and temporary night blindness. Congenital night blindness is mostly related to congenital genetic factors, where patients inherently lack the ability to synthesize rhodopsin, leading to night blindness. Acquired night blindness is often due to diseases of the retina or other eye diseases, and it is recommended to actively treat the primary disease. Temporary night blindness is mostly due to a lack of Vitamin A in the diet, or due to certain digestive system diseases affecting Vitamin A absorption, and it is advised to supplement Vitamin A and other treatments as prescribed by a doctor.