What medicine should be taken for intrahepatic bile duct stones?

Written by Zhang Tao
Hepatobiliary Surgery
Updated on September 10, 2024
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The treatment of intrahepatic bile duct stones currently does not have specific medications. Traditional Chinese medicine treatments primarily focus on clearing the liver and facilitating bile flow, and have certain clinical effects. Western medicine often uses deoxycholic acid, ursodeoxycholic acid, and chenodeoxycholic acid, which can somewhat prevent the formation of bile duct stones. It is also recommended that patients change poor lifestyle habits, adjust their life rhythms, and eat three meals a day at regular times, especially breakfast. Specific medications should be used under the guidance of a doctor.

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Written by Liu Wu Cai
Hepatobiliary Surgery
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Is the likelihood of malignant transformation of intrahepatic bile duct stones high?

Intrahepatic bile duct stones have a relatively low probability of becoming cancerous. Patients with intrahepatic bile duct stones may develop acute cholangitis, presenting with symptoms like severe pain in the upper right abdomen, nausea, vomiting, jaundice, and systemic infectious symptoms such as chills and high fever, but generally, these stones do not become cancerous. When patients with intrahepatic bile duct stones exhibit significant symptoms, it is important to take them seriously and perform timely surgical treatment to achieve a radical cure. The main surgical approach is laparoscopic salpingotomy for stone removal, which can lead to better treatment outcomes. Additionally, dietary adjustments should include avoiding spicy and irritating foods to reduce inflammatory stimuli and better prevent exacerbation of the condition.

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Written by Zhang Tao
Hepatobiliary Surgery
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Can intrahepatic bile duct stones be shattered?

Asymptomatic intrahepatic bile duct stones generally do not require treatment. Currently, most hepatobiliary surgeons believe that if patients undergo shock wave lithotripsy, the stones may migrate to the extrahepatic bile duct, forming common bile duct stones, and the patient will experience obvious abdominal pain, jaundice, and other symptoms, causing great trouble. Therefore, they oppose extracorporeal shock wave treatment for intrahepatic bile duct stones and suggest regular follow-up with ultrasound or CT, adopting more reasonable methods for treatment.

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Written by Liu Wu Cai
Hepatobiliary Surgery
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Do intrahepatic bile duct stones fear cold?

Patients with intrahepatic bile duct stones can possibly experience chills. This is because patients with intrahepatic bile duct stones often have concurrent cholangitis, which manifests as chills, high fever, prominent upper abdominal pain, and jaundice. In severe cases, it can even lead to acute suppurative cholangitis, septic shock, and death. Therefore, for patients with intrahepatic bile duct stones presenting with significant symptoms, early surgical treatment is advised. Surgery involves opening the bile duct to remove the stones, which can be curative. Post-surgery, it is still necessary to avoid spicy and irritating foods, such as peppers, barbecues, and garlic, and to mainly consume a bland diet with plenty of fresh vegetables and fruits to facilitate recovery. After recovery, patients generally do not experience significant discomfort.

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Written by Shen Jiang Chao
Radiology
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Intrahepatic bile duct stones B-ultrasound manifestations

Intrahepatic bile duct stones show typical sonographic changes on ultrasound, appearing as punctate or mass-like strong echoes within the liver, accompanied by acoustic shadows. These strong echoes are distributed along the intrahepatic bile ducts. The bile duct proximal to the stone may exhibit varying degrees of dilation, and the dilated intrahepatic bile duct, along with the accompanying portal vein, forms a parallel tube sign. Around the strong echoes of the stones, a narrow anechoic region can be seen encircling them, and the stones generally do not move with changes in body position. Intrahepatic bile duct stones can also cause thickening of hepatic parenchyma echoes and internal echo heterogeneity.

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Written by Zhang Tao
Hepatobiliary Surgery
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Symptoms of intrahepatic bile duct stones

Intrahepatic bile duct stones, depending on the duration and pathology, can present with various clinical manifestations. In the early stages, patients generally do not show obvious symptoms, with stones limited to a certain segment within the intrahepatic bile ducts. In later stages, stones can be found throughout the intra- and extrahepatic biliary system, and may even lead to biliary cirrhosis, liver atrophy, and liver abscesses. The clinical manifestations can include: first, pain in the upper abdomen; second, a long history of biliary tract diseases, with patients experiencing chills, fever, and jaundice; third, frequent pain and discomfort in the liver area on the affected side and the lower chest, which can radiate to the shoulder and back, etc.