Symptoms of severe pancreatitis

Written by Wei Shi Liang
Intensive Care Unit
Updated on September 26, 2024
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The main symptom of severe pancreatitis is abdominal pain. This type of abdominal pain manifests as intense pain in the upper-middle abdomen, which radiates to the back and both sides of the body. The pain is widespread and severe, with about 95% of patients experiencing abdominal pain. Onset often occurs following binge eating or excessive drinking, and the pain worsens after eating. Another symptom is abdominal distension, which is also a common symptom. It is caused by extensive effusion in the abdominal cavity and retroperitoneum, as well as intestinal paralysis. Fever in the early stage of the disease is also a common symptom, resulting from the absorption of a large amount of necrotic tissue. Fever occurring in the later stages is often caused by infections triggered within the abdominal cavity.

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What medicine is used for pancreatitis?

In clinical practice, it is advised that patients with pancreatitis be hospitalized for treatment. The primary medications used during hospitalization mainly involve nutritional support, as patients with pancreatitis cannot eat and must refrain from ingesting food and water, necessitating the supplementation of water and electrolyte balance. Treatment primarily consists of using medications that reduce pancreatic secretion, such as choosing octreotide or similar drugs. Other drugs can be combined to inhibit pancreatic enzyme activity. However, while using these medications, it is important to consider using antibiotics to prevent infections in cases of pancreatitis. Overall, it is crucial to receive standardized treatment in a hospital for pancreatitis, as the condition can change rapidly and is relatively dangerous. (The use of medications should be under the guidance of a doctor.)

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Can I drink tea with pancreatitis?

Patients with pancreatitis are advised not to drink tea. If the symptoms are severe, they might experience intense abdominal pain, stomach coldness, fever, and cessation of gas and bowel movements. Under these conditions, patients should not drink water or eat anything, and certainly should not drink tea. The causes of pancreatitis could be biliary stone-related inflammation, excessive drinking or eating, or due to alcohol consumption. A minority of cases might be due to anatomical abnormalities of the pancreas or autoimmune diseases. Therefore, once pancreatitis occurs, it is necessary to identify the cause and take appropriate treatment measures. This includes actively suppressing the secretion of pancreatic enzymes and stomach acid, aggressively rehydrating, and, if necessary, undergoing surgical treatment.

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How to check for pancreatitis?

The examination of pancreatitis requires laboratory tests and imaging examinations to assess the severity of the condition and to identify the cause. Elevated amylase and lipase levels more than three times the normal values, increased white blood cells, elevated C-reactive protein, increased blood sugar, elevated transaminases and bilirubin, decreased albumin, increased urea nitrogen and creatinine, decreased blood oxygen partial pressure, decreased blood calcium, elevated triglycerides, and abnormalities in blood sodium, potassium, and pH values all reflect the severity of pancreatitis. Abdominal ultrasound is a routine initial screening imaging examination for acute pancreatitis, and abdominal CT is helpful in confirming the presence of pancreatitis, peripancreatic inflammatory changes, and pleural effusion. Enhanced CT is beneficial in determining the extent of pancreatic necrosis and is generally performed about a week after the onset of the condition. However, when searching for the cause of pancreatitis, the sensitivity and accuracy of CT are not as good as MRI, therefore further MRI should be conducted to investigate causes related to the bile duct and to determine the cause of the pancreatitis.

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Where does pancreatitis hurt?

Pancreatitis generally presents as abdominal pain, specifically in the upper abdomen, the area above the navel, and near the xiphoid process. The pain is usually continuous and may intensify intermittently. Some patients also experience intolerable radiating pain in the lumbar and back areas, which can improve when they bend over. Patients commonly experience nausea and vomiting, which typically involve stomach contents without blood. Some patients may also have a fever, most commonly a low-grade fever between 37°C and 38.5°C. Patients usually seek medical attention for abdominal pain, and the pain in the upper abdomen and back area is a common complaint. To further clarify the diagnosis, patients typically need to undergo tests such as amylase evaluation, abdominal CT, and abdominal ultrasound. After these tests, a diagnosis of pancreatitis can usually be made. Treatment initially focuses on symptomatic management and medical treatment.

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Causes of Pancreatitis

Common causes of pancreatitis in clinical settings include biliary tract diseases, alcohol consumption, overeating, and hyperlipidemia, among others, with biliary tract diseases being the most common. Pancreatitis is generally defined as inflammatory changes in the pancreas due to self-digestion caused by various reasons. Clinical manifestations include abdominal pain, bloating, nausea, and vomiting, etc. Therefore, for patients with upper abdominal pain, it is necessary to further complete some examinations, such as liver function, amylase, lipase, abdominal ultrasound, and even abdominal CT scans, to clarify the diagnosis, which is generally straightforward for pancreatitis. The treatment of pancreatitis, in addition to symptomatic treatment, requires etiological treatment, combining different causes of pancreatitis. For instance, if caused by hyperlipidemia, lipid-lowering treatment is generally needed; if biliary tract disease is considered, active treatment of the biliary disease is required.