Prickly heat and eczema have significant differences and are completely different from each other. First, prickly heat is generally caused by high local temperatures, or hot and humid conditions, leading to the appearance of papules and rashes on the skin. Eczema, on the other hand, is often caused by multiple factors, such as climate, environment, diet, and contact with certain substances, and is a type of allergic inflammatory response. Secondly, the treatment for prickly heat generally involves the application of prickly heat powder or similar products, which can lead to improvement and cure. Eczema, however, is often treated with astringent or corticosteroid ointments. If the effect is average, treatment may also include the oral intake of antihistamines.