"Does a weakly positive Mycoplasma pneumoniae indicate pneumonia?"

Written by Han Shun Li
Pulmonology
Updated on January 03, 2025
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During the testing process, if Mycoplasma pneumoniae shows a weakly positive result, this does not necessarily indicate that the person has pneumonia. A weakly positive result for Mycoplasma pneumoniae only suggests a possible infection, but does not confirm pneumonia. If there is a suspicion, further investigation, such as chest radiography, should be conducted. If chest radiography reveals changes in lung patterns or patchy areas in the lungs, then it can be considered that the person may have Mycoplasma pneumoniae pneumonia. If the chest radiography is normal, it cannot be concluded that the person has pneumonia.

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Differential Diagnosis of Pediatric Pneumonia

Childhood pneumonia needs to be differentiated from other respiratory diseases such as bronchial foreign bodies, bronchial asthma, and pulmonary tuberculosis. A bronchial foreign body generally has a history of inhalation of foreign objects, sudden choking coughs, and a chest X-ray might indicate atelectasis or pulmonary emphysema. If the foreign body has been present for a long time, the disease course is prolonged and may lead to secondary infections, similar to pneumonia or concurrent with pneumonia. The differentiation of bronchial foreign body involves detailed medical history inquiries to check for inhaled foreign objects, then using symptoms and auxiliary examinations like chest X-rays for confirmation. Bronchial asthma, especially in children, might not always present with obvious wheezing attacks but rather persistent coughing. The X-ray might show increased and disordered lung markings and pulmonary emphysema, which can easily be confused with pneumonia. Typically, children with bronchial asthma have an allergic constitution and generally require pulmonary function tests and other auxiliary examinations to differentiate from pneumonia. Pulmonary tuberculosis generally occurs in those with a history of contact with tuberculosis patients. Their tuberculin skin test is positive, and X-rays may show features of tuberculosis lesions in the lungs, which can be used to differentiate from pneumonia.

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Is the pneumonia vaccine self-funded?

The pneumonia vaccine is primarily aimed at preventing pneumonia caused by Streptococcus pneumoniae infection. Streptococcus pneumoniae is the most significant and common bacterium causing pneumonia worldwide. This bacterium is also the most common cause of community-acquired pneumonia in children and is the main pathogen causing otitis media, meningitis, and bacteremia in children. Currently, there are two types of pneumonia vaccines available in China: the 23-valent polysaccharide vaccine, which is suitable for people over two years old, and the 7-valent vaccine, which is suitable for infants under two years old. According to the regulations on vaccine distribution and vaccination management implemented in our country, vaccines are clearly divided into two categories: the first category includes vaccines provided free by the government to citizens, who are required to be vaccinated according to government regulations; the second category includes other vaccines that are paid for and voluntarily received by citizens. The pneumonia vaccine belongs to the second category, which is a self-funded vaccine.

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Can pneumonia be cured?

Can pneumonia be cured, and will there be any sequelae? Generally speaking, common pneumonia without complications can be completely cured. If pneumonia infection is detected, seek medical attention in a timely manner and treat it rationally under the guidance of a professional doctor, it generally will not leave sequelae or affect lung function. However, some complications of pneumonia, such as meningitis and pericarditis, may leave symptoms like headaches, dizziness, palpitations, and chest pain. Ordinary pneumonia might leave streaky shadows or irregular pleura on chest X-rays or lung CT scans, but these will not impact the human body. Patients who have previously been infected with tuberculosis may have calcification spots in their lungs, which is a normal phenomenon. Some people may experience sequelae after treatment, such as hearing loss caused by the use of antimicrobial drugs, and avascular necrosis of the femoral head occurring after SARS treatment; however, these are possibly side effects of the drugs, rather than sequelae of pneumonia.

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Is pneumonia serious?

Is pneumonia serious, and what will happen if it worsens or goes untreated? Severe pneumonia can lead to septic shock and can even be life-threatening. If pneumonia is not treated or not treated thoroughly, it can deteriorate into the following conditions: First, it can cause lung abscesses and empyema, and even lead to pericarditis, meningitis, and more; Second, the infection can enter the bloodstream, causing bacteremia and even septic shock; Third, the patient's continuous high fever can lead to febrile convulsions and even the possibility of coma; Fourth, extensive pneumonia can reduce the function of the alveoli, causing hypoxia and carbon dioxide retention. Hypoxia can affect the function of the nervous system, and patients with severe pneumonia may experience drowsiness, irritability, and even convulsions and coma.

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How to completely cure pneumonia in children?

Childhood pneumonia is mainly due to the weaker resistance of children, who are then subjected to the invasion of pathogens such as bacteria, viruses, or other agents like chlamydia and mycoplasma, leading to inflammation of the alveoli. Generally, the treatment of pneumonia is mainly targeted at its pathogens. For instance, antiviral treatment is administered for viral infections, antibacterial and anti-inflammatory treatments are required for bacterial infections, and specific antibiotics such as azithromycin or erythromycin are used for mycoplasma infections. For other types like tuberculosis and some other fungal pneumonias, specific treatments targeting those pathogens are also necessary. If the baby clearly has symptoms like wheezing or difficulty in breathing, symptomatic treatment is required. Therefore, pneumonia in children is mainly treated based on the cause, and as long as the course of treatment is sufficient, it can be cured completely. However, even after recovery, it does not mean a child will never contract pneumonia again. If the child has weak immunity or is in a high-risk environment with exposure to other patients with pneumonia cough, they might be infected again.