What does the early rash of lupus look like?

Written by Liu Li Ning
Rheumatology
Updated on November 30, 2024
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The early characteristic rash of lupus erythematosus is typically a butterfly-shaped rash on the face. Other common presentations include palm and periungual erythema, discoid rash, nodular erythema, and livedo reticularis. If the rash is not notably itchy, it generally indicates lupus erythematosus. If there is significant itching, it may suggest the possibility of an allergic factor active in the disease. After immunosuppression, itchy rashes should be monitored for possible fungal infections. The specific pathogenesis of systemic lupus erythematosus is still unclear. If a patient exhibits the typical butterfly-shaped rash on the face, systemic lupus erythematosus should be highly suspected. Testing for antinuclear antibodies, and specifically for anti-Sm and double-stranded DNA antibodies, which represent a variety of autoantibodies, can diagnose systemic lupus erythematosus.

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Written by Zhang Lin
Rheumatology and Immunology Nephrology
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What should I do if lupus causes hair loss?

What should be done when a lupus patient experiences hair loss? Patients with lupus should keep their hair clean in daily life, not use too much shampoo when washing their hair, avoid dyeing or perming their hair, and reduce the damage to hair from chemical products. This prevents rashes or worsening rashes caused by allergies to hair dyes and damage to hair quality from perming. If hair loss occurs due to the effect of medications, patients can choose to wear a wig during treatment. After chemotherapy ends, new hair will grow, so patients need not worry excessively. Maintaining a pleasant mood is also quite important for recovery from the disease. The basic pathological change in lupus patients is vasculitis. When the small blood vessels in the skin become inflamed, the nutrient supply to the hair follicles is disrupted, which can easily lead to hair loss and affect hair growth. Generally, hair can regrow after the disease is controlled. If hair loss occurs again, it could be a symptom of a disease relapse.

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Written by Zhang Lin
Rheumatology and Immunology Nephrology
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Does lupus cause itchy skin?

The rash in patients with lupus erythematosus is generally not noticeably itchy. In patients with lupus erythematosus, the characteristic changes include a butterfly-shaped rash on the bridge of the nose and cheeks. The skin lesions of lupus erythematosus include photosensitivity, hair loss, erythema on the palms and soles and around the nails, discoid lupus, nodular erythematosus, seborrheic dermatitis, livedo reticularis, and Raynaud's phenomenon, among others. Generally, there is no noticeable itching. If significant itching occurs, it suggests an allergy. Itchy rash after immunosuppressive treatment should be monitored for fungal infections. Lupus patients receiving steroid and immunosuppressive therapy, if experiencing unexplained localized skin burning, may be showing early signs of herpes zoster and should seek prompt medical attention at a hospital.

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Written by Zhang Lin
Rheumatology and Immunology Nephrology
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Can lupus be cured?

Lupus erythematosus currently has no cure in clinical practice. However, an early diagnosis and treatment can significantly prolong the life expectancy of patients. Compared to the past, with standardized and effective individualized treatments, the 5-year survival rate can reach 95%, and the 10-year survival rate can reach 84%. However, the cause of lupus erythematosus is unclear, and no method can completely cure the disease. It is important to emphasize that there are already some medications available clinically that can alleviate the symptoms, allowing patients to live normal lives and work normally. Additionally, it is crucial not to resort to desperate measures by seeking random treatments or believing in folk remedies and secret family recipes shared by others. Such actions can not only delay proper treatment and waste money but also worsen the condition due to unclear formulations.

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Written by Zhang Lin
Rheumatology and Immunology Nephrology
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What causes lupus erythematosus?

The cause of lupus erythematosus is not yet very clear. It is generally believed that the disease is caused by a combination of factors including genetics, environment, estrogen levels, and drugs, leading to immune disorder and consequently the onset of this disease. Studies have found that factors directly related to the onset of lupus erythematosus include ultraviolet rays causing apoptosis of epidermal cells, exposure of new antigens becoming autoantigens, and infections; Other possible related factors include drugs such as hydralazine and isoniazid, as well as food dyes, hair dyes, celery, figs, mushrooms, smoked foods, psychological stress, etc.; it may also be related to factors such as tobacco, vinyl chloride, asbestos, and vaccinations.

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Written by Zhang Lin
Rheumatology and Immunology Nephrology
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For lupus, register under the department of Rheumatology.

Patients with lupus should visit the Department of Rheumatology and Immunology, as lupus is a clinically complex autoimmune disease. Many people think that lupus is a skin disease, but this is not the case. Lupus is a rheumatic and immunological disease, belonging to the category of rheumatic immunological diseases, and is an uncommon autoimmune disease.