Typical symptoms of lymphoma

Written by Zhou Zi Hua
Oncology
Updated on September 13, 2024
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Typical symptoms of lymphoma include night sweats, fever, and weight loss. This fever often occurs in the afternoon, characterized as a cyclical fever that lasts for several days with irregular patterns. There are fever-free intervals ranging from a few days to several weeks, almost a nonspecific symptom but not commonly seen. Fever, night sweats, and unexplained weight loss of more than 10% within six months, or even emaciation, are considered B symptoms and are associated with a poor prognosis. In addition, skin itching is also not uncommon in late-stage patients.

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What to check for malignant lymphoma?

The examination of lymphoma first requires routine blood tests and blood smears. When aggressive lymphoma invades the bone marrow, anemia, decreased white blood cells, and platelets may occur, and lymphoma cells can appear in peripheral blood; therefore, bone marrow smears and biopsies are necessary. Additionally, blood biochemistry is important, as an increase in lactate dehydrogenase is associated with tumor burden and is an indicator of poor prognosis. Furthermore, Hodgkin's lymphoma may involve the central nervous system, so patients with symptoms of central nervous system involvement need to undergo cerebrospinal fluid examination. The most important aspect of lymphoma is the histopathological examination. Based on the histopathological examination, the pathological staging is determined, and genetic rearrangement can also be performed.

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How to rule out lymphoma in children

Lymphoma is a malignant tumor originating from the lymphatic system. The main clinical manifestation is painless lymph node enlargement, which can occur in superficial lymph nodes such as in the neck, armpits, or groin, as well as deeper lymph nodes in the mediastinum or abdominal cavity. In pediatric patients with lymphoma, a significant number also present with abdominal pain, intestinal obstruction, or intussusception, which often indicates intestinal lymphoma. If children exhibit lymph node enlargement or deep lymph node enlargement is discovered through imaging studies, it is necessary to perform a puncture or biopsy and conduct a pathological examination to further confirm whether it is lymphoma.

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Written by Liu Liang
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Can lymphoma be cured?

Whether lymphoma can be cured depends on the specific pathological type of lymphoma, as there are dozens of subtypes, each with different prognoses and sensitivities to treatment. Additionally, the stage of lymphoma in patients also affects the prognosis. For example, patients with early-stage lymphoma can achieve a cure through radiotherapy and chemotherapy. However, for patients with advanced-stage lymphoma, treatment primarily involves chemotherapy, especially in cases of highly aggressive lymphoma, where it is difficult to achieve a complete cure. The goal of treatment in such cases is to alleviate pain and extend the patient's life.

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What are the symptoms of lymphoma?

The symptoms of lymphoma usually involve painless, progressive enlargement of the lymph nodes, typically located in areas like the neck, under the jaw, and below the chin. However, beyond these localized symptoms, lymphoma can also present with systemic symptoms, which include fever, night sweats, weight loss, as well as rashes and itching skin. Thus, lymphoma encompasses both local and systemic symptoms.

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Does lymphoma infect family members?

Lymphoma and other malignant tumors, such as lung cancer, breast cancer, intestinal cancer, liver cancer, etc., are all non-contagious. Therefore, even if you live with your family every day, you do not have to worry about transmitting malignant tumors to your family members; they are not contagious. When we refer to contagious diseases, we call them infectious diseases, common ones include tuberculosis, hepatitis B, hepatitis C, H1N1, etc. These are contagious diseases, but malignant tumors are not contagious and will not be spread to family members.