Symptoms of Uremia

Written by Li Liu Sheng
Nephrology
Updated on December 13, 2024
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Once diagnosed with uremia, patients exhibit numerous clinical symptoms, though these symptoms are not completely identical across different individuals. Typically, the primary symptoms of uremia include nausea, vomiting, loss of appetite, with these symptoms becoming more pronounced after eating. There might even be diarrhea, an increase in the frequency of bowel movements, and gastrointestinal bleeding. Additionally, patients show signs of edema, particularly around the eyelids and face, with very noticeable swelling in the lower limbs. Severe cases may also present with pleural effusion and ascites, accompanied by a reduction in urine output. Patients may also experience dizziness, headache, elevated blood pressure, and even exhibit pallor, anemia, itchy skin, bone pain, and intolerance to cold, among various other clinical symptoms.

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Written by Li Liu Sheng
Nephrology
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Causes of Uremia

Uremia is a syndrome caused by the progressive development of various chronic kidney diseases that ultimately leads to bilateral renal failure in patients, unable to timely remove excess water, electrolytes, and various toxins from the body. The causes of uremia are many and complex. Common causes include chronic nephritis, diabetic nephropathy, and hypertensive nephropathy. Other diseases such as chronic interstitial nephritis, chronic pyelonephritis, uric acid nephropathy, chronic obstructive nephropathy, renal vascular diseases, and hereditary nephritis can also lead to uremia. Once uremia occurs, patients often exhibit symptoms of general discomfort and may need to choose dialysis treatment, which can be either hemodialysis or peritoneal dialysis, depending on individual circumstances.

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Written by Guan Hai Fang
Urology
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Is uremia serious?

Uremia is very serious. For patients with uremia who wish to be cured, the current method is to undergo kidney transplantation. Kidney transplantation is currently considered the best method for treating uremia. If no suitable kidney source is found, or economic conditions do not allow, or for some other reasons, it is recommended that patients undergo dialysis. Dialysis is also quite expensive, but if economic conditions permit, and physical health and mood among other factors allow, patients with uremia who undergo regular dialysis can generally have their lives extended by several years. It is not uncommon to see reports of lives being extended by more than a decade.

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Written by Tang Da Wei
General Surgery
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Can holding urine lead to uremia?

Holding urine will not cause uremia. Holding urine may lead to bladder fullness, and after a long time, it might cause dilation of the ureters, but it will not lead to uremia. Uremia is caused by renal insufficiency or end-stage renal failure, characterized by significantly increased creatinine and urea nitrogen in the patient's body, with reduced urine output or even anuria. Once uremia is diagnosed, it generally requires hospitalization for dialysis treatment, which involves removing toxins from the body through dialysis. Additionally, it is advised to consume nutritionally rich foods in daily life.

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Written by Huang Feng Fei
Urology
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Why would someone get uremia?

Uremia, also known as end-stage renal failure, has many causes. Common surgical conditions include urological obstructions such as urethral blockage, kidney tumors, malformations, kidney cancer, and others, as well as numerous kidney cysts, all of which can lead to renal failure. Common internal medicine causes include chronic glomerulonephritis, long-standing hypertension, hypertensive nephropathy, diabetes, diabetic nephropathy, etc., which can also lead to renal failure. In summary, end-stage renal failure is referred to as uremia.

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Written by Guan Hai Fang
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Is uremia cancer?

Uremia is not cancer. Chronic kidney failure refers to the presence of various kidney diseases that lead to a progressive and irreversible decline in kidney function, culminating in a series of symptoms and metabolic disorders that form a clinical syndrome, commonly known as chronic kidney failure. The end stage of chronic kidney failure is what is often referred to as uremia. Uremia is not a separate disease, but a clinical syndrome common to various late-stage kidney diseases. It is a symptom consisting of a series of clinical manifestations that occur when chronic kidney failure enters its terminal stage. Typically, this includes disturbances in water and electrolyte acid-base metabolism, with metabolic acidosis and water-electrolyte imbalance being the most common.