Causes of Uremia

Written by Li Liu Sheng
Nephrology
Updated on October 19, 2024
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Uremia is a syndrome caused by the progressive development of various chronic kidney diseases, eventually leading to renal failure in patients, where the kidneys are unable to promptly eliminate excess water, various electrolytes, and toxins from the body. There are many causes of uremia; chronic nephritis, diabetic nephropathy, and hypertensive nephropathy are the most common causes. Other causes include chronic tubulointerstitial nephritis, chronic pyelonephritis, chronic obstructive nephropathy, toxic nephropathy, hereditary nephritis, renal vascular diseases, and lupus nephritis. Once uremia occurs, the preferred treatment is dialysis therapy, which can be either hemodialysis or peritoneal dialysis. Only after dialysis treatment can the life of a patient with uremia be prolonged.

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Written by Zhou Qi
Nephrology
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What should I do about uremia heart failure?

Patients with uremia often develop complications of heart failure, which is actually the leading cause of death in patients with uremia. This type of heart failure is mainly due to the decreased ability of the kidneys to excrete water, leading to an increase in blood volume and an increased burden on the heart. It is also related to many factors such as the patient often having hypertension, anemia, coronary heart disease, etc. For such diseases, it is first necessary to assess whether the patient has excess water in the body. If there is too much water, urgent dialysis ultrafiltration is needed to remove the water. After the water is removed, the symptoms of heart failure will be significantly relieved. Secondly, it is necessary to deal with some other complications related to heart failure. For example, in the case of anemia, temporary blood transfusions or the use of erythropoiesis-stimulating agents to promote hematopoiesis can be used. Hypertension requires the use of antihypertensive drugs to control blood pressure and other comprehensive treatment measures. (Please use medications under the guidance of a doctor)

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Written by Zhou Qi
Nephrology
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Is uremia hereditary?

Uremia is not actually an independent disease, so it's difficult to say that uremia is hereditary. Uremia refers to a condition where the kidneys are 90% damaged. However, there are many reasons that can cause more than 90% of kidney tissue damage; among these, some are genetic diseases, but most are not hereditary. Common causes of hereditary uremia include diabetes, as well as primary chronic glomerulonephritis, hypertension, urinary system stones, and even prostate tumors, allergic purpura, etc., which can all cause kidney damage. These factors are generally not genetic diseases. However, there are very few causes of uremia that are genetic diseases, mainly including autosomal dominant polycystic kidney disease.

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Written by Li Liu Sheng
Nephrology
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Causes of Uremia

Uremia is a syndrome caused by the progressive development of various chronic kidney diseases that ultimately leads to bilateral renal failure in patients, unable to timely remove excess water, electrolytes, and various toxins from the body. The causes of uremia are many and complex. Common causes include chronic nephritis, diabetic nephropathy, and hypertensive nephropathy. Other diseases such as chronic interstitial nephritis, chronic pyelonephritis, uric acid nephropathy, chronic obstructive nephropathy, renal vascular diseases, and hereditary nephritis can also lead to uremia. Once uremia occurs, patients often exhibit symptoms of general discomfort and may need to choose dialysis treatment, which can be either hemodialysis or peritoneal dialysis, depending on individual circumstances.

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Written by Guan Hai Fang
Urology
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Is uremia serious?

Uremia is very serious. For patients with uremia who wish to be cured, the current method is to undergo kidney transplantation. Kidney transplantation is currently considered the best method for treating uremia. If no suitable kidney source is found, or economic conditions do not allow, or for some other reasons, it is recommended that patients undergo dialysis. Dialysis is also quite expensive, but if economic conditions permit, and physical health and mood among other factors allow, patients with uremia who undergo regular dialysis can generally have their lives extended by several years. It is not uncommon to see reports of lives being extended by more than a decade.

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Written by Wang Shuai
Urology
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Is hematuria the same as uremia?

Hematuria is not the same as uremia; hematuria is merely a symptom with various causes such as infections of the urinary system, tumors, stones, or decreased coagulation function leading to blood in the urine. After experiencing hematuria, it is necessary to promptly visit a hospital's urology department for routine urine tests, ultrasonography of the urinary system, CT scans, urinary system imaging, or even a cystoscopy to determine the specific cause of the hematuria. Uremia, on the other hand, primarily refers to damage to kidney function, leading to decreased kidney function, which causes symptoms such as reduced urine output and localized edema in the body. If hematuria occurs or uremia is suspected, a detailed examination at the hospital's urology or nephrology department is required promptly.