Precursors of acute appendicitis

Written by Ren Zheng Xin
Gastroenterology
Updated on September 02, 2024
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Acute appendicitis is acute inflammation of the appendix lumen, and currently, there are no particularly typical precursors, but the causes of acute appendicitis should be noted, which are related to obstruction and infection of the appendix cavity. If the appendix lumen is compressed for a long time, the accumulation of secretions can cause blood supply disorders in the distal appendix wall, directly causing damage to the appendix mucosa, and inducing infection that leads to appendicitis. Additionally, gastrointestinal dysfunctions such as diarrhea and constipation can also cause spasms of the appendix muscles and vessels, leading to blood supply disorders and mucosal damage, thereby causing acute appendicitis.

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Written by Ren Zheng Xin
Gastroenterology
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The etiology of acute appendicitis

The main cause of acute appendicitis is due to the narrowing of the appendiceal lumen, which can easily lead to the obstruction of food residues and fecal masses. Following the obstruction, mucosal damage occurs, which leads to secondary infections. Additionally, neglecting regular living habits, such as overeating, excessive fatigue, and frequent heavy drinking can exacerbate or trigger acute appendicitis. Therefore, maintaining regular living habits in daily life, such as having meals at fixed times, reasonable rest and work schedules, balancing work and leisure, and engaging in appropriate outdoor activities, can play a positive role in preventing acute appendicitis.

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Symptoms of acute appendicitis

The typical symptoms of acute appendicitis include abdominal pain that starts around the upper abdomen or navel area, then localizes to the lower right abdomen. There are also manifestations of gastrointestinal spasms such as nausea and vomiting. Due to inflammation entering the bloodstream, there can be a systemic infection, often accompanied by fever, generally not exceeding 38 degrees Celsius. If there is an appendix perforation and peritonitis, the temperature can exceed 38 degrees. After the appendix becomes suppurative, symptoms can include abdominal muscle rigidity, dental pain, and rebound tenderness.

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Gastroenterology
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Causes of Acute Appendicitis

The main causes of acute appendicitis are obstruction of the appendiceal lumen and concurrent infection. The appendiceal lumen is a narrow tube that communicates with the cecum at one end. Obstruction, such as a fecalith, can lead to increased pressure inside the lumen, disturbances in blood flow, damage to the mucosa, and secondary infection. It can also be caused by direct bacterial infection within the appendiceal lumen, leading to acute inflammation. Additionally, repeated diarrhea or constipation and other gastrointestinal dysfunctions can also cause circulation disturbances in the appendix, leading to bacterial invasion and acute inflammation.

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Which is more serious, acute appendicitis or chronic appendicitis?

The symptoms of acute appendicitis are relatively more severe because acute suppurative appendicititis can cause perforation of the appendiceal lumen. After the perforation, pus can flow into the abdominal cavity causing diffuse peritonitis, leading to abdominal muscle tension, tenderness, and rebound pain. If not treated promptly, it can lead to multiple organ failure. Chronic appendicitis is mostly due to incomplete treatment of acute appendicitis, or chronic latent appendicitis. The symptoms of chronic appendicitis are sometimes mild and the physical signs are not definite. Surgical removal of the appendix should be the first choice for treating acute appendicitis.

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Written by Ren Zheng Xin
Gastroenterology
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Typical symptoms of acute appendicitis

The typical symptoms of acute appendicitis include abdominal pain, which starts in the upper abdomen or around the navel and, after several hours, shifts and localizes to the lower right abdomen. Additionally, reflexive gastric spasms may cause nausea and vomiting. Due to the inflammation, the body may develop a fever, generally not exceeding 38 degrees Celsius. If the inflammation affects the parietal peritoneum, it can cause tenderness, rebound pain, and abdominal muscle rigidity. These are the typical symptoms, and a preliminary diagnosis can usually be made based on them. Most cases require an appendectomy.