Why do benign teratomas recur?

Written by Yan Chun
Oncology
Updated on December 10, 2024
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Benign teratomas, although not aggressive or metastatic, do not require adjuvant chemotherapy or radiation therapy after curative surgery to fight the tumor. However, many benign teratomas recur after surgery and require further surgical treatment. The cause of benign teratoma recurrence is considered to be due to the persistent presence of oncogenic factors. Therefore, benign tumors can also recur, since the exact cause and pathogenesis of benign teratomas are still unclear clinically. Thus, prevention from an etiological perspective is not possible, and the only option is timely surgical removal upon tumor detection to prevent the benign teratoma from becoming malignant. For patients with benign teratomas, regular follow-up is necessary after curative surgery to monitor any changes in the condition. If signs of recurrence are detected, prompt intervention is necessary to prevent malignancy.

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Written by Li Shun Hua
Obstetrics and Gynecology
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Does ovarian teratoma affect menstruation?

Ovarian teratomas include mature teratomas, which are benign tumors. These benign ovarian teratomas do not affect menstruation. However, there are also malignant teratomas, which are immature teratomas. Immature teratomas can secrete hormones, and because they secrete different types of hormones, their impact on menstruation varies. If an ovarian teratoma is diagnosed, immediate surgical treatment is required, because if it is an immature teratoma, it is malignant. Prolonged presence can lead to metastasis. If a teratoma is detected early, early-stage malignant tumors can be cured through surgical treatment.

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Written by Liu Jian Wei
Obstetrics and Gynecology
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What are the symptoms of a teratoma?

Patients with teratomas may have no clinical symptoms whatsoever. Some women only discover ovarian teratomas incidentally during gynecological ultrasound examinations at health check-ups. However, it is important to note that if ovarian teratomas develop complications, they can present a range of clinical symptoms. For example, if an ovarian teratoma undergoes torsion, the patient may experience lower abdominal pain, accompanied by nausea and vomiting. Moreover, if the teratoma has malignant tendencies, it can exhibit a series of clinical manifestations typical of malignant tumors.

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Written by Yan Qiao
Obstetrics and Gynecology
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What to do about teratoma pain in the lower abdomen?

Patients with teratomas experiencing lower abdominal pain require immediate attention. Due to the uneven texture of the teratoma itself, it can easily lead to torsion of the ovarian tumor pedicle as a result of changes in the patient's body position. Ovarian tumor pedicle torsion is a gynecological emergency requiring urgent surgical intervention. This is particularly crucial for young women who have not yet given birth, as early surgery can preserve the affected ovary, potentially improving future fertility chances. For older women, emergency surgery to relieve symptoms is also extremely important. Therefore, abdominal pain in patients with teratomas must be taken seriously.

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Written by Zhang Xiu Rong
Obstetrics and Gynecology
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Does teratoma affect menstruation?

Teratoma, under normal circumstances, does not affect menstruation, but it does affect fertility. If it is confirmed that one side has a teratoma, surgery is generally required. After treatment, the ovary on that side is typically removed. Once removed, that ovary will no longer ovulate, and ovulation must occur from the other ovary. The maintenance of hormone levels in the body needs to be supported by the other ovary. If the function of the other ovary is normal, menstruation will continue to occur normally; it will not affect menstruation. However, if after the removal of the teratoma, one ovary is removed, the chance of conception is reduced by half compared to others. Therefore, it is crucial for patients with teratoma to undergo surgery as early as possible. After the surgery, if the pathology shows no issues and if it is a simple teratoma removal, it does not affect menstruation.

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Written by Li Shun Hua
Obstetrics and Gynecology
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Will a teratoma regrow if it is removed?

After surgery for ovarian teratoma, whether it can regrow is uncertain, because ovarian tissue can potentially develop such tumors. Ovarian teratomas can be benign or malignant. The recurrence rate of benign teratomas is very low after surgery, but there is still a possibility of regrowth. However, for malignant teratomas, also known as immature teratomas, surgery involves removing the affected ovary. The opposite ovary can be preserved if it is normal, depending on the patient's age, but regular follow-ups are necessary. If the patient is older, an extensive surgery for teratoma, which includes the removal of both the uterus and ovaries, might be required.