Teratoma Benign and Malignant Differences

Written by Hou Jie
Obstetrics and Gynecology
Updated on November 28, 2024
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Teratoma refers to a common type of germ cell tumor, which can be classified into mature teratomas and immature teratomas. Mature teratomas are benign tumors, accounting for 10%-20% of ovarian tumors. They can occur at any age but are more common between the ages of 20 and 40. Most are unilateral, of moderate size, and usually have a single compartment filled with sebum and hair; sometimes teeth and bone can also be found. Immature teratomas, on the other hand, are malignant tumors, making up 1%-3% of ovarian teratomas. These are more frequent in younger patients, with an average age of 11 to 19 years. The ovaries are predominantly solid but may include cystic areas, primarily consisting of primitive neural tissue. The malignancy level of the ovary depends on the proportion of immature tissue, the degree of differentiation, and the content of neuroepithelial tissue.

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Written by Liu Wei Jie
Obstetrics
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Is it easy to get pregnant with a teratoma?

First, what is a teratoma? Teratoma is a common ovarian tumor in gynecology, with a very high incidence rate. It is generally benign and the occurrence of teratomas is related to congenital genetic factors. Generally, if a teratoma is found, the first step is to check the size of the teratoma. If it is smaller than five centimeters, tumor series tests are normal, and there is no other discomfort, observation can be initiated. If the teratoma is relatively large, larger than five centimeters, surgical intervention is required. Teratomas themselves are not related to pregnancy, but because teratomas can lead to ovarian cyst torsion, after torsion occurs, one side of the adnexa may need to be removed, which could reduce fertility.

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Written by Du Rui Xia
Obstetrics
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Does teratoma affect fetal development?

Teratomas are not normal fetuses; they are a type of tumor originating from germ cells in the ovaries. Pregnancy will not affect the normal development of the baby, and regular prenatal check-ups at the hospital are advisable. If it is possible to surgically remove the teratoma before trying to conceive, it is best to do so. Teratomas can be benign or malignant. Benign teratomas contain various components, including skin, hair, teeth, and bones. Malignant teratomas are poorly differentiated and more prone to malignant transformations and metastasis.

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Written by Liu Jian Wei
Obstetrics and Gynecology
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Do ovarian teratomas hurt?

Ovarian teratomas do not cause abdominal pain under normal conditions. However, if a patient engages in vigorous activities, it can lead to a torsion of the ovarian teratoma. The torsion of the teratoma can drag the ovary to twist along with it, consequently affecting the blood supply to the adnexa on the affected side, leading to ischemic necrosis of the adnexa, and thus causing a sudden onset of severe lower abdominal pain on one side. In such abnormal situations, the ovarian teratoma can indeed cause lower abdominal pain.

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Written by Zhang Xiu Rong
Obstetrics and Gynecology
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Does teratoma affect menstruation?

Teratoma, under normal circumstances, does not affect menstruation, but it does affect fertility. If it is confirmed that one side has a teratoma, surgery is generally required. After treatment, the ovary on that side is typically removed. Once removed, that ovary will no longer ovulate, and ovulation must occur from the other ovary. The maintenance of hormone levels in the body needs to be supported by the other ovary. If the function of the other ovary is normal, menstruation will continue to occur normally; it will not affect menstruation. However, if after the removal of the teratoma, one ovary is removed, the chance of conception is reduced by half compared to others. Therefore, it is crucial for patients with teratoma to undergo surgery as early as possible. After the surgery, if the pathology shows no issues and if it is a simple teratoma removal, it does not affect menstruation.

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Written by Yue Hua
Obstetrics and Gynecology
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Is a teratoma pregnancy?

Teratoma is not a pregnancy; it is a type of ovarian tumor. Most of the time, this tumor is benign. It commonly occurs in individuals aged between 20 and 40 years. The formation of teratomas is generally due to poor differentiation during the embryonic stage, resulting in the development of this type of tumor. Very occasionally, teratomas can become malignant, which requires high vigilance. Most cases of malignancy are seen in young females aged between 11 and 19. Malignant teratomas are usually solid, but they can also have cystic areas.