Why does a teratoma have hair?

Written by Liu Jian Wei
Obstetrics and Gynecology
Updated on November 17, 2024
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Mature teratomas contain lipids, hair, and even bone and other tissue structures within the tumor cavity. The main reason for this is that teratomas are composed of cells from multiple embryonic layers. These embryonic layer cells can develop in different directions, further developing into tissues such as hair, lipids, or bones. Therefore, during surgical procedures, it is common to find hair within the teratoma.

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Written by Du Rui Xia
Obstetrics
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Are ovarian teratomas congenital?

Ovarian teratomas are congenital, primarily deriving from primordial germ cells. Teratomas consist of tissues from multiple embryonic layers, mostly being immature types. Most ovarian teratomas are cystic. Depending on the degree of tissue differentiation, teratomas can be classified as benign or malignant. Benign teratomas, also known as mature teratomas, are more common in women aged 20-40 and are usually unilateral and either round or ovoid in shape. A portion of these teratomas are malignant, typically found in younger patients, roughly aged 11-19 years, and this condition has a poorer prognosis, requiring timely surgical treatment.

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Written by Liu Jian Wei
Obstetrics and Gynecology
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Do ovarian teratomas hurt?

Ovarian teratomas do not cause abdominal pain under normal conditions. However, if a patient engages in vigorous activities, it can lead to a torsion of the ovarian teratoma. The torsion of the teratoma can drag the ovary to twist along with it, consequently affecting the blood supply to the adnexa on the affected side, leading to ischemic necrosis of the adnexa, and thus causing a sudden onset of severe lower abdominal pain on one side. In such abnormal situations, the ovarian teratoma can indeed cause lower abdominal pain.

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Written by Xu Xiao Ming
Obstetrics and Gynecology
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What are the symptoms of teratoma?

Ovarian teratomas can cause abdominal pain and might even result in sudden abdominal enlargement, often accompanied by symptoms like bloating. Women experiencing these symptoms are advised to seek medical attention promptly. Ovarian teratomas are more commonly found in younger women, particularly during their reproductive years. Thus, female patients experiencing these symptoms should promptly undergo an ultrasound at a hospital to check for the presence of teratomas and also have a blood test for tumor markers. If a teratoma is present, it is recommended to undergo surgical treatment as soon as possible due to the risk of malignant transformation.

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Written by Shen Li Wen
Obstetrics and Gynecology
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What is the cause of the pain from a teratoma?

Female teratomas are cystic-solid tumors located on the ovaries. When they are small in size, they generally do not cause pain. However, as they grow larger, due to gravitational pull, they stretch the surrounding ligaments, causing women to experience hidden pain on one side of the lower abdomen. This pain is bearable and only intensifies after vigorous activities or intercourse. Some women may experience increased pain if they have a pelvic infection or during menstruation. Because teratomas are uneven in texture, if they are not adherent to surrounding structures and are relatively mobile, and their stalk is thinner, they might twist under certain circumstances, such as rolling over, spinning hula hoops, or during pregnancy, when the uterus grows and changes the position of the teratoma, leading to acute lower abdominal pain from torsion of the teratoma’s stalk. Therefore, when a woman experiences abdominal pain from a teratoma, it is essential to conduct a gynecological examination and pelvic ultrasound to understand the specific cause of the pain.

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Written by Xu Xiao Ming
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Does teratoma require blood tests?

If a patient with a teratoma needs to undergo a blood test, the blood test may include routine blood work and blood biochemistry, as well as tumor marker tests such as CA125 and alpha-fetoprotein (AFP) to check for any abnormal increases. If surgery is required for the patient, there might be additional blood tests conducted, including lipid profile, thyroid function tests, and infection and immunity tests. All these require blood draws for the examination.