What medicine is used to stop bleeding in the upper gastrointestinal tract?

Written by Zhu Dan Hua
Gastroenterology
Updated on October 31, 2024
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Pharmacological treatment for upper gastrointestinal bleeding may include aggressive fluid resuscitation to improve symptoms of hypovolemia, transfusion of red blood cells when necessary to correct anemia, and the use of acid-suppressive and gastroprotective medications to prevent further bleeding. Common causes of upper gastrointestinal bleeding include gastric ulcers, duodenal ulcers, and even vascular anomalies. Therefore, in the early stages, it is advisable to choose acid-suppressive and gastroprotective medications to treat common causes such as gastric ulcers and gastritis, which lead to bleeding. The main symptoms of upper gastrointestinal bleeding are vomiting blood or bleeding from the bowels. In severe cases, the patient may also experience dizziness and fatigue due to low blood volume. For such patients, once the condition stabilizes, it is important to conduct routine blood tests, electrocardiography, and gastroscopy to identify the specific cause of the bleeding. Different causes require different treatment approaches. If the bleeding is suspected to be caused by a tumor, pharmacological treatment may not be very effective, and surgical intervention might be more appropriate. (The use of medications should be under the guidance of a doctor.)

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Written by Wang Li Bing
Intensive Care Medicine Department
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Which department should I go to for upper gastrointestinal bleeding?

The upper gastrointestinal system primarily refers to bleeding from the digestive system above the Treitz ligament. Therefore, if there is acute massive bleeding in the digestive tract, patients may present with symptoms such as vomiting blood and black stools. If the bleeding is significant and blood volume rapidly decreases, it can cause acute peripheral circulatory disorders, and may even be life-threatening. The causes of upper gastrointestinal bleeding include long-standing conditions like peptic ulcers, rupture of esophagogastric varices, acute erosive hemorrhagic gastritis, and stomach cancer, among others. If upper gastrointestinal bleeding occurs, patients should actively seek medical attention at major hospitals' gastroenterology departments, undergo relevant examinations, and receive prompt treatment.

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Written by Wang Li Bing
Intensive Care Medicine Department
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Upper gastrointestinal bleeding gastroscopy time

Upper gastrointestinal bleeding is also relatively common in clinical practice. The most common causes are bleeding from peptic ulcers, rupture of esophageal and gastric varices, bleeding caused by gastric cancer, and various emergency bleedings. Once gastrointestinal bleeding occurs, medical attention should be sought promptly. If the patient experiences hemorrhagic shock or hemorrhagic anemia, it is necessary to provide blood transfusions and hemostasis, and replenish blood volume as active treatments. Additionally, for upper gastrointestinal bleeding, it is generally advisable to complete a gastroscopic examination within 24 to 48 hours, which can help clarify the cause of the patient’s gastrointestinal bleeding.

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Written by Wang Li Bing
Intensive Care Medicine Department
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Upper digestive tract bleeding vomit color

The color of vomit in upper gastrointestinal bleeding primarily relates to the amount of bleeding and the speed of bleeding. If the patient has minor bleeding, the gastric acid may process it, resulting in the vomiting of a coffee-ground-like substance, indicating a smaller amount of bleeding. If the patient has substantial bleeding at a rapid pace, surpassing the gastric acid processing, fresh blood may often be vomited, indicating significant bleeding and a poor prognosis. After upper gastrointestinal bleeding occurs, it is crucial to seek medical attention immediately. In clinical settings, patients are usually given proton pump inhibitors and somatostatin analog drugs to stop the bleeding, and it is vital to promptly conduct a thorough gastroscopy to ascertain the causes of gastrointestinal bleeding and so forth.

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Written by Wang Li Bing
Intensive Care Medicine Department
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Upper gastrointestinal bleeding clinical manifestations

Upper gastrointestinal bleeding primarily refers to bleeding above the Treitz ligament. The most common causes in clinical practice are peptic ulcers, rupture of esophagogastric varices, acute erosive hemorrhagic gastritis, gastric cancer, etc. The clinical manifestations of upper gastrointestinal bleeding mainly depend on the volume and speed of the bleeding, with the main symptoms being vomiting blood and black stools. After significant blood loss, patients may experience symptoms of peripheral circulatory failure due to reduced circulating blood volume, such as dizziness, palpitations, fatigue, cold limbs, increased heart rate, and low blood pressure. If the patient enters a state of shock, it could even be life-threatening.

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Written by Wang Li Bing
Intensive Care Medicine Department
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How to treat upper gastrointestinal bleeding?

After gastrointestinal bleeding, the patient should be kept in a recumbent position to rest and ensure that the airway is clear to avoid aspiration of blood due to vomiting. Close monitoring of the patient's vital signs, such as heart rate, blood pressure, and breathing, is necessary. It is important to actively replenish blood volume, correct hypovolemic shock, and administer medications for hemostasis. Endoscopic hemostasis with a gastroscope can also be used. If conservative drug treatment is not effective, surgical treatment may be considered. Emergency treatment is essential after gastrointestinal bleeding, as delays can be life-threatening.