What medicine is used to stop bleeding in the upper gastrointestinal tract?

Written by Zhu Dan Hua
Gastroenterology
Updated on October 31, 2024
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Pharmacological treatment for upper gastrointestinal bleeding may include aggressive fluid resuscitation to improve symptoms of hypovolemia, transfusion of red blood cells when necessary to correct anemia, and the use of acid-suppressive and gastroprotective medications to prevent further bleeding. Common causes of upper gastrointestinal bleeding include gastric ulcers, duodenal ulcers, and even vascular anomalies. Therefore, in the early stages, it is advisable to choose acid-suppressive and gastroprotective medications to treat common causes such as gastric ulcers and gastritis, which lead to bleeding. The main symptoms of upper gastrointestinal bleeding are vomiting blood or bleeding from the bowels. In severe cases, the patient may also experience dizziness and fatigue due to low blood volume. For such patients, once the condition stabilizes, it is important to conduct routine blood tests, electrocardiography, and gastroscopy to identify the specific cause of the bleeding. Different causes require different treatment approaches. If the bleeding is suspected to be caused by a tumor, pharmacological treatment may not be very effective, and surgical intervention might be more appropriate. (The use of medications should be under the guidance of a doctor.)

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Written by Zhu Dan Hua
Gastroenterology
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Upper gastrointestinal bleeding refers to bleeding that occurs in the upper gastrointestinal tract.

Upper gastrointestinal bleeding generally refers to bleeding caused by esophageal, gastric, and duodenal lesions, which clinically manifests most commonly as vomiting blood and blood in stools. Of course, some patients may also experience symptoms such as dizziness, fatigue, and chest tightness. Common causes to be aware of include inflammation, ulcers, tumors, and vascular malformations, especially gastric and duodenal ulcers which are relatively common in clinical settings. The fastest diagnosis mainly relies on gastroscopy, thus it is recommended that patients who suspect upper gastrointestinal bleeding should undergo a gastroscopy as soon as their condition stabilizes to determine the specific cause of the bleeding, such as digestive tract ulcers or even tumors. For treatment, conservative medical management is initially advised, focusing on aggressive fluid replenishment, acid suppression for gastric protection, and blood volume supplementation. Once the gastroscopy provides a clear diagnosis, the treatment plan should be promptly adjusted.

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Written by Zhu Dan Hua
Gastroenterology
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Clinical manifestations of upper gastrointestinal bleeding

Patients with upper gastrointestinal bleeding typically present with vomiting blood or bleeding from the stool. Of course, if the bleeding amount is small, there may be no other discomfort. However, if the bleeding is significant, symptoms may include dizziness, fatigue, chest tightness, and palpitations related to low blood volume. Some patients might also experience abdominal discomfort, such as abdominal pain, bloating, or even indigestion. For those suspected of upper gastrointestinal bleeding, it is advisable to further complete blood tests, stool analysis, and electrocardiograms. It is necessary to promptly carry out a gastroscopy when needed to clarify the cause of the bleeding, and consider if it is due to ulcers or vascular malformations. In the early stages of treatment, symptomatic management should be prioritized, and patients are advised to actively rehydrate to improve symptoms of low blood volume and to transfuse red blood cells if necessary to correct anemia. Once the cause is identified, causative treatment should be added, such as the use of acid-suppressing and gastric-protecting drugs for bleeding associated with peptic ulcers. (The use of medications should be under the guidance of a doctor.)

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Written by Wang Li Bing
Intensive Care Medicine Department
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Common Causes of Upper Gastrointestinal Bleeding

The common causes of upper gastrointestinal bleeding mainly include the following points: First, esophageal diseases, such as esophagitis, Mallory-Weiss syndrome. Secondly, peptic ulcers, gastric cancer, acute erosive hemorrhagic gastritis, and then esophageal gastric variceal rupture caused by portal hypertension. There are also diseases of neighboring organs or tissues of the upper digestive tract, such as biliary bleeding, pancreatic diseases involving the duodenum, such as pancreatic cancer, acute pancreatitis complicated by abscess rupture and bleeding. Additionally, there are systemic diseases, such as allergic purpura, hemophilia, leukemia, etc.

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Written by Wang Li Bing
Intensive Care Medicine Department
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Is upper gastrointestinal bleeding dangerous?

Upper gastrointestinal bleeding is life-threatening if the amount and speed of bleeding are substantial. Therefore, proactive and effective measures should be taken to rescue the patient. Generally, after anti-shock treatment and rapid blood volume replenishment, the patient's life can be saved. The main clinical treatment measures include the following: First, keep the patient in a recumbent position at rest, ensure that the airway is clear, and prevent blood aspiration due to vomiting. Second, during the bleeding period, it is necessary to enforce fasting, closely monitor the patient's vital signs, such as heartbeat, breathing, blood pressure, consciousness, etc. Third, after hospitalization, it is crucial to actively replenish blood volume, such as transfusing compatible red blood cells, plasma, cryoprecipitate, etc., for fluid expansion. Drugs like proton pump inhibitors and octreotide can be used for hemostasis. If conditions permit, a gastroscopy can be performed to stop the bleeding, and surgical treatment may be considered if necessary.

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Written by Wu Hai Wu
Gastroenterology
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Can you eat egg custard with upper gastrointestinal bleeding?

As for whether one can eat egg custard when experiencing upper gastrointestinal bleeding, it requires specific analysis of the situation. If it is during the acute phase of bleeding, such as just after vomiting blood, at that moment, one cannot eat anything and must fast. If the upper gastrointestinal bleeding has been treated and the patient has largely recovered, then they can eat egg custard, as well as other liquid or semi-liquid foods. Therefore, whether a patient with upper gastrointestinal bleeding can eat egg custard depends on the patient's condition. Once a patient experiences upper gastrointestinal bleeding, it is crucial to seek prompt medical attention at a reputable hospital's gastroenterology department to undergo thorough examinations, such as an endoscopy, to confirm the diagnosis.