Can ovarian cancer be cured?

Written by Liu Liang
Oncology
Updated on September 15, 2024
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Whether ovarian cancer can be cured depends on the clinical stage of the patient, as well as the patient's sensitivity to treatment, among other factors. If it is a case of early-stage ovarian cancer, curative surgery can be performed. After surgery, based on the pathology, it can be decided whether postoperative adjuvant radiotherapy or chemotherapy is necessary. Patients with early-stage ovarian cancer who undergo surgery or postoperative adjuvant radiotherapy and chemotherapy may have hope for a cure. However, if the cancer is discovered at a late stage where it has spread extensively, such as widespread metastasis to the pelvic area, or even to distant organs like the lungs or liver, then the treatment for these patients is primarily chemotherapy. A cure is not achievable; the treatment aims to alleviate symptoms and prolong the patient's life. Thus, for patients with late-stage ovarian cancer, treatment cannot achieve a curative purpose.

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Written by Liu Liang
Oncology
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How is ovarian cancer diagnosed?

Ovarian cancer is discovered through transvaginal ultrasound of the adnexa uteri revealing ovarian tumors, or through imaging studies such as abdominal CT scans or MRIs showing ovarian tumors, combined with tumor markers, particularly the ovarian epithelial cancer tumor marker CA125, which will be significantly elevated. Generally, with these findings, ovarian cancer can typically be clinically diagnosed. Confirmation, however, requires pathological diagnosis, which involves obtaining a biopsy of the tumor. This can be done through a puncture biopsy or through pathological examination after surgical excision to confirm ovarian cancer. Additionally, some patients with ovarian cancer present with substantial ascites at the time of discovery. If cancer cells are found in the abdominal fluid, combined with a significant increase in CA125 and imaging studies showing ovarian tumors, ovarian cancer can also be diagnosed.

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Written by Liu Liang
Oncology
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How is ovarian cancer screened?

The most commonly used screening method for ovarian cancer is the B-ultrasound examination of the adnexa uteri. The B-ultrasound can detect ovarian masses and tumors, and when these are found, the possibility of ovarian cancer should be considered, necessitating further examinations for confirmation. Another method involves the tumor marker CA125, which is relatively sensitive and specific for epithelial ovarian cancer. Therefore, for ovarian cancer screening, we can perform a blood test for CA125 in conjunction with a B-ultrasound of the adnexa uteri.

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Written by Liu Liang
Oncology
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Location of abdominal pain in ovarian cancer

Ovarian cancer in patients manifests as tumors in either both ovaries or one ovary. Therefore, the abdominal pain they experience is lower abdominal pain, not bloating or sudden, noticeable increase in abdominal size. Additionally, the primary pathway for the metastasis of ovarian cancer is through implantation, allowing widespread metastatic implants in the pelvic and abdominal cavities. There is also local spread of the tumor to the uterus, fallopian tubes, and surrounding pelvic tissues. Thus, the location of abdominal pain in ovarian cancer is in the lower abdomen, specifically pain and bloating in the pelvic area.

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Written by Yan Chun
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What are the early symptoms of ovarian cancer?

Patients with ovarian cancer often do not exhibit many symptoms in the early stages, and many do not have obvious symptoms initially. Some patients may experience pelvic pain due to tumor growth early on, primarily located in the bilateral pelvic area, with some experiencing pain that radiates to the perineal area. Some early-stage ovarian cancer patients may experience abnormalities in their menstrual cycle, primarily manifested as irregular menstruation, increased menstrual flow, and the presence of blood clots. Some patients may also experience abnormal vaginal bleeding outside of their menstrual period. In addition, some patients in the early stages may exhibit signs of abnormal hormone secretion. Aside from these, most early-stage ovarian cancer patients do not show obvious symptoms.

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Ovarian cancer requires the following examinations:

The examination for ovarian cancer begins with an abdominal ultrasound, which can clarify the tumor's size, shape, cystic or solid nature, location, and its relationship with neighboring organs. If necessary, CT scans and MRI can be conducted for a clearer view. Next are tumor markers, which are essential in the diagnosis of ovarian cancer. Additionally, CT scans of the lungs and head, or MRI, and a complete blood count of bone can help rule out distant metastasis. The most critical part is the pathological diagnosis, as the definitive diagnosis of tumors primarily relies on pathology. We can obtain a clear pathological diagnosis through laparoscopy or exploratory laparotomy.