Oral cancer can generally be detected through HPV testing. For tumors in our head and neck regions, it is currently believed that the HPV positivity rate is relatively higher in tumors occurring in the oropharynx and hypopharynx areas. There are several methods for HPV testing: one is testing the HPV virus itself, and another is testing for the P16 protein. Therefore, detection can be carried out through throat swabs, saliva, and bodily fluids, which can identify the virus and determine which types are high-risk and which are subtypes, and then look at the P16 protein to see if there are pathological tissues, detecting the negativity or positivity of this P16 protein through pathological tissues.