Will a stage 1 kidney cancer recurrence occur after nephrectomy?

Written by Wang Jian
Urology
Updated on March 15, 2025
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Stage I kidney cancer generally belongs to early-stage kidney cancer, which usually presents no symptoms and is most often discovered during physical examinations. This is the case for more than 50%-60% of kidney cancers. The examination for kidney cancer also requires a CT scan of the kidney and an enhanced CT scan to confirm the diagnosis. If it is stage I, the cure rate through surgical removal is very high. Surgical operation is the first choice for treating kidney cancer and is recognized as a means to cure kidney cancer. Early-stage kidney cancer can be treated with laparoscopic or traditional open surgery, which involves a radical removal of the kidney. For patients with stage I kidney cancer, the five-year survival rate can reach about 92%. Post-surgery, regular follow-up visits are necessary to check for recurrence, metastasis, and new tumors. After surgery, stage I kidney cancer patients should have follow-up visits every three to six months for the first three years and annually thereafter. Stage I kidney cancer has a chance of being completely cured but also the possibility of recurrence, so regular follow-ups are essential.

Other Voices

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Written by Zou De Bo
Urology
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What are the characteristic symptoms of kidney cancer?

Most kidney cancer patients are discovered during health check-ups, and these patients may account for over 50%-60% of all kidney cancer cases. Among those with symptoms, the most common symptoms are lower back pain and blood in urine. A few patients also present with abdominal masses. 10%-40% of patients can exhibit paraneoplastic syndromes, manifested as high blood pressure, anemia, weight loss, cachexia, fever, abnormal liver function, hyperglycemia, increased erythrocyte sedimentation rate, and other changes. Additionally, symptoms such as bone pain, fractures, cough, and coughing blood can occur due to tumor metastasis.

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Written by Xu Chun Hua
Urology
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Survival rate after early removal of kidney cancer

The prognosis of renal cancer is closely related to its clinical staging. If it is in the early stages, surgery is the preferred treatment and the prognosis is very good. Timely surgery followed by subsequent treatments such as immunotherapy, targeted therapy, etc., is recommended. For early-stage renal cancer, the five-year survival rate after surgical removal can exceed 90%, and some patients may live without issues for over 20 years. How long someone lives specifically also depends on the individual's constitution and physical condition.

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Written by Zou De Bo
Urology
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The difference between benign and malignant kidney cancer.

The incidence of kidney cancer is also considered relatively high, with over 95% of kidney tumors being malignant, and benign tumors being less common. The distinction between benign and malignant tumors is determined by their symptomatic expression and growth patterns, and they have different impacts on the body. Generally, benign tumors grow expansively or exophytically, have a slower growth rate, and have clearer boundaries with often a capsule surrounding them. The texture and color of the tumor are close to that of normal tissues. Malignant tumors, on the other hand, exhibit the opposite characteristics.

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Written by Wang Shuai
Urology
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Clinical Manifestations of Renal Cancer

In the early stages of kidney cancer, most patients do not experience any discomfort symptoms, making it difficult to detect. As the tumor progresses to the middle and late stages and increases in size, it can cause symptoms of back pain. If the tumor breaches the renal pelvis, leading to ruptured blood vessels, this condition will be accompanied by obvious gross hematuria, which often appears intermittently and is painless. If the tumor is large, a mass can be felt in the back. If these symptoms arise, it is crucial to promptly visit the hospital's urology department for tests such as ultrasound and CT scans to establish a clear diagnosis. If necessary, active surgical intervention should be considered.

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Written by Zou De Bo
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Difference between Renal Cancer and Renal Pelvis Cancer

First, the sites of the disease are different; renal pelvis cancer usually occurs in the epithelium of the renal pelvis or calyces, while renal cancer typically originates from the epithelial cells of the renal tubules. Second, the presentations are different; hematuria is a common symptom of both renal pelvis cancer and renal cancer. However, in renal pelvis cancer, hematuria can occur early, while in renal cancer, hematuria may not be seen until the tumor has invaded the renal pelvis or calyces. Third, the diagnostic tests are different; the clinical diagnosis of renal cancer heavily relies on CT scans, whereas renal pelvis cancer primarily depends on excretory or retrograde urography, that is, CT urography. Fourth, the CT appearances are different; on CT scans, renal cancer typically shows as a multicystic lesion with more pronounced enhancement during contrast than that seen in renal pelvis cancer. Fifth, the results of cytological examinations are different; cytology of renal pelvis cancer may show positive tumor cells, but renal cancer might test negative.