kidney cancer immunotherapy drugs

Written by Xu Chun Hua
Urology
Updated on September 19, 2024
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The immunotherapy for kidney cancer often involves the use of interferons or interleukins, and the results are generally satisfactory. The effects of radiotherapy and chemotherapy for kidney cancer are not very certain. Typically, after kidney cancer is diagnosed, radical nephrectomy is performed. During the surgery, adequate exposure is essential. The renal hilum should be ligated first to prevent cancer cells from being squeezed into the bloodstream during surgery. It is also necessary to remove the fascia and fat around the kidney, along with the lymph nodes at the renal hilum. Combining these surgical measures with immunotherapy usually yields very ideal results.

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Ultrasound manifestation of renal cancer

Kidney cancer is the most common type of kidney malignancy. Pathologically, it is mainly divided into clear cell renal cell carcinoma, chromophobe renal cell carcinoma, papillary renal carcinoma, and collecting duct carcinoma, with clear cell renal cell carcinoma being the most common. Ultrasonographically, it usually appears as round or oval masses, varying in size but generally around 2-4 cm, exhibiting low to medium echo patterns. If the tumor is larger, greater than 5 cm, it may show changes in mixed echo patterns due to possible internal bleeding or cystic changes when the tumor is large. When kidney cancer is suspected on ultrasound, it is best to further proceed with enhanced MRI or enhanced CT scanning.

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What are the characteristics of hematuria in renal cancer?

What we commonly refer to as kidney cancer actually includes two aspects. One is renal cell carcinoma, and the other is renal pelvis cancer or ureteral cancer. The characteristics of hematuria are different in these two types. Renal cell carcinoma, simply understood, grows inside the kidney and is not connected with urine. Only when the kidney tumor grows large enough to breach the kidney or renal pelvis will the tumor rupture and bleed, causing hematuria. This generally occurs in the middle to late stages of kidney cancer. On the other hand, renal pelvis cancer or ureteral cancer exhibits intermittent hematuria in the early stages without significant symptoms, but as it progresses to the middle and late stages, symptoms like kidney hydronephrosis and hematuria slowly appear. When diagnosing these conditions, any occurrence of hematuria must be investigated to determine the cause. Initial screening can be done using urinary system ultrasound, urinalysis, or routine urine tests. More precise methods include enhanced CT or MRI of the urinary system, which facilitate easier diagnosis.

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Can you have sexual intercourse after kidney cancer removal?

After kidney cancer removal, based on an individual's physical condition, sexual activity can still be undertaken. Radical nephrectomy is also the best treatment method. During the surgery, it is often necessary to fully expose the area, first ligating the renal pedicle to prevent squeezing cancer cells into the bloodstream during surgery, while also removing the fascia and fat around the kidney, along with the lymph nodes at the hilum. After the surgery, it is also necessary to complement this with immunotherapy, such as using interferons and interleukins for immune treatment. Patients with kidney cancer can engage in appropriate sexual activities after surgery, but they should not be too strenuous, aiming not to feel tired the following day.

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The typical three major symptoms of kidney cancer

The typical three major symptoms of kidney cancer are hematuria, pain, and a mass. If these three symptoms appear, it generally indicates that the condition has reached an advanced stage, at which point the patient may have missed the optimal timing for treatment. Surgery at this stage may also be challenging to perform completely. Therefore, early detection and treatment are essential. The five-year survival rate after kidney cancer surgery is as high as 97% for many people. Thus, overall, the prognosis for kidney cancer is relatively good. However, the best treatment approach remains surgery, including nephron-sparing surgery and radical nephrectomy, depending on the size of the tumor. Generally, for tumors smaller than four centimeters, nephron-sparing treatment can be adopted.

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Is kidney cancer prone to metastasis?

Kidney cancer in its early stages generally does not metastasize. If it does metastasize, it usually follows several paths: one is hematogenous or lymphatic spread, followed by local diffusion, and then the tumor invades surrounding fat or blood vessels, which is local diffusion. It is also important to note that there is a pseudo-capsule around the kidney cancer that prevents the spread of cancer cells. Metastasis is not likely when the tumor is small, but as the tumor size increases or in some special types of tumor cells, metastasis may occur.