How to prevent premature rupture of membranes?

Written by Wang Jing Hua
Obstetrics and Gynecology
Updated on February 14, 2025
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The prevention of premature rupture of membranes primarily involves preventing infection. This is because the main cause of premature rupture of membranes is likely due to infection, though it can also be due to pelvic issues and irregular uterine contractions that stimulate the rupture. Therefore, those with a history of premature rupture of membranes should undergo relevant examinations early in pregnancy and receive prenatal care routinely, including tests for vaginal secretions. Even if one feels no discomfort, it is advisable to conduct an examination for vaginal pathogens and, if necessary, begin medication early. (Medication should be used under the guidance of a professional doctor.)

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Written by Zhang Lu
Obstetrics
1min 12sec home-news-image

Can premature rupture of membranes heal?

Premature rupture of membranes refers to the rupture of the membranes before labor, causing the leakage of amniotic fluid. In clinical practice, once premature rupture of membranes is confirmed, it is impossible for the membranes to heal again, as currently, there are no methods available to repair or suture the membranes. The treatment for premature rupture of membranes mainly involves preserving the pregnancy, suppressing contractions, and anti-infection therapy, without any expectation of curing the condition by healing the ruptured membranes. Once ruptured, the membranes cannot be healed again. Some patients, after experiencing premature rupture of membranes, may suddenly find that they are no longer leaking amniotic fluid and believe that it has healed. This scenario could be possible for several reasons: the first is that premature rupture of membranes may have not occurred in the first place, and the previous vaginal discharge could have been vaginal secretions; the second is that the amniotic fluid volume might be very low, with little amniotic fluid leaking out, which is a dangerous situation that requires prompt termination of the pregnancy.

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Written by Du Rui Xia
Obstetrics
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What should I do if the membranes rupture prematurely?

If it occurs before the baby is full-term and there is premature rupture of membranes, efforts should be made to preserve the pregnancy and prolong its duration. It is necessary to rest in bed, maintain cleanliness of the external genitalia, and closely monitor the condition of vaginal discharge, contractions, and whether the mother has any infections. If more than 12 hours have passed since the rupture of membranes, antibiotics should be administered to prevent infection, which can help prevent neonatal pneumonia and also reduce the occurrence of intracranial hemorrhage in the baby, as well as decrease the incidence of chorioamnionitis and postpartum endometritis. Medications that inhibit uterine contractions should be used if contractions occur. Additionally, medications that promote the maturation of the fetal lungs should be used to prevent preterm birth, which can lead to breathing difficulties.

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Written by Liu Wei Jie
Obstetrics
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Premature rupture of membranes causes

The causes of premature rupture of membranes, or premature rupture of membranes, occur before labor when the membranes break. Normally, the membranes should rupture during labor when the cervix is fully dilated. Any rupture before this is called premature rupture of membranes. The main causes of premature rupture of membranes are maternal infections or cephalopelvic disproportion. Infections can cause the membranes to become fragile and thin, and movements afterwards may lead to premature rupture. Another scenario is cephalopelvic disproportion, where the fetus is relatively large and the pelvis is small, leading to changes in amniotic fluid pressure, which can also result in premature rupture of membranes.

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Written by Zhang Lu
Obstetrics
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Is premature rupture of membranes prone to infection?

After premature rupture of membranes, various aspects of impact on both the mother and the fetus can occur, but the most important is the risk of infection. After the rupture of membranes, since the amniotic cavity is connected to the vagina through the cervix, the bacteria present in the vagina can potentially enter the amniotic cavity through the cervix and cause an infection inside the amniotic cavity. Therefore, after the rupture of membranes, the most crucial action is to prevent infection, primarily using antibiotics for treatment and closely monitoring indicators of infection. Monitoring for infection after premature rupture of membranes can be done in the following ways: first, pay attention to the characteristics of the amniotic fluid, which often has an odor in case of infection; second, monitor infection indicators, including white blood cells and C-reactive protein; third, observe if the pregnant woman exhibits any symptoms of fever.

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Written by Zhang Lu
Obstetrics
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Premature rupture of membranes symptoms

Premature rupture of membranes, as the name implies, refers to the clinical symptoms caused by the rupture of the amniotic sac before labor. These symptoms include the following aspects. First, there will be a leakage of amniotic fluid from the vagina, manifesting as wet pants or a wet bedsheet, which is a primary indication of premature rupture of membranes. Second, when the membranes rupture prematurely, there is often a small amount of bloody show. This is mainly because there are small capillaries on the membranes that also bleed when the membranes rupture, causing blood to mix with the amniotic fluid. Third, premature rupture of membranes often is accompanied by significant contractions, as the increase in pressure within the amniotic cavity during contractions can cause the membranes to rupture. When these situations occur, it is important to promptly go to the hospital to undergo an ultrasound and gynecological examination to confirm whether there is a premature rupture of membranes.